NEW YORK (Reuters Health)—Two classes of inflammatory diseases, uveitis and psoriatic disease, appear linked, as a diagnosis of one increases the risk of developing the other, new research has found.
A study of Danish patient registries found nearly triple the rate of uveitis among patients with psoriatic arthritis compared to the general population, and double among patients with severe psoriasis. Likewise, patients with uveitis had a four-fold higher rate of psoriatic arthritis and more than double the rate of severe psoriasis, according to research published online July 29 in JAMA Dermatology.
“Fortunately, the absolute number of patients with psoriasis who develop uveitis, and vice versa, is low. However, increased focus on eye symptoms in patients with psoriasis and on skin and joint symptoms in patients with prior or current uveitis may be appropriate,” lead author Dr. Alexander Egeberg, of Gentofte Hospital at the University of Copenhagen, Denmark, told Reuters Health by email.
The evaluation included about 5.5 million patients over a 15-year period. Among them, Dr. Egeberg and colleagues found 74,129 cases of psoriasis and psoriatic arthritis and 13,114 cases of uveitis.