In its second indication in the EU, ixekizumab has been approved by the European Commission to treat adults with active psoriatic arthritis…
Family Planning Counseling & the Rheumatologist
Women with rheumatic diseases have unique reproductive health needs, and family planning counseling is a critical component to their overall healthcare. A new research review examines the barriers to patients with rheumatic disease receiving family planning counseling. Additionally, reviewers provide rheumatologists with practical suggestions to optimize communication with patients, as well as address the effect of medications and the effectiveness of contraception…
Baseline Bone Measures Predict Risk of Fragility Fracture in Postmenopausal
NEW YORK (Reuters Health)—Baseline measures of bone density, microarchitecture and strength predict the risk of fragility fractures in postmenopausal women, according to results from the Calgary CaMOS cohort. Changes in bone health were not associated with fracture risk, however, said Dr. Lauren A. Burt from the University of Calgary, Canada, who worked on the study….
New Recommendations Guide Imaging in Large-Vessel Vasculitis
NEW YORK (Reuters Health)—Patients with suspected large-vessel vasculitis (LVV) should undergo early imaging, the European League Against Rheumatism (EULAR) advises in a new report presenting a dozen evidence-based recommendations for the use of imaging in primary LVV. Ultrasound should be the first choice for giant-cell arteritis (GCA), while MRI should take precedence for Takayasu arteritis…
Mouse Model Suggests Regulatory T Cells Play Important Role in Sjögren’s Syndrome Pathophysiology
Recent research investigated the progression and characteristics of Sjögren’s syndrome using mice engineered to lack special genome organizing AT-rich sequence binding protein-1 (SATB1). These mice proved to be a novel model for Sjögren’s syndrome and revealed T cell-dominant immune cell infiltration of the salivary glands. Over time, the frequency of B cells gradually increased, as well as the levels of anti-SSA and anti-SSB antibodies…
Upadacitinib Receives Breakthrough Designation, Abatacept Use Expands in Australia & More
The FDA has designated upadacitinib a breakthrough therapy to treat adults with moderate to severe atopic dermatitis…
Service Dogs Aid RA Patients with Mobility, Chores, Companionship & More
Patients with severe RA can struggle with walking, getting dressed, carrying items and more, all of which can negatively affect their quality of life. But according to Bharat Kumar, MD, service dogs can help RA patients by providing both physical and emotional support, aiding patient mobility and quality of life…
Arthritis More Common Than Previously Thought
Arthritis prevalence in the U.S. population has been substantially underestimated, especially among adults younger than 65.
Circulating MicroRNA Provides Clues to Class IV Lupus Nephritis
A recent study has shed light on the role of circulating microRNAs (miRNAs) in SLE pathogenesis. In particular, patients with lupus nephritis have an abundance of 24 miRNAs, many of which play a role in regulatory feedback loops…
Higher Fracture Risk in Patients with Polymyalgia Rheumatica, Giant-Cell Arteritis
NEW YORK (Reuters Health)—Patients with polymyalgia rheumatica (PMR) and giant-cell arteritis (GCA) have similarly increased risks of fracture, compared with the general population, researchers have found. “It is of surprise that patients with GCA have a similar fracture risk to those with PMR,” Dr. Zoe Paskins from Keele University, in Staffordshire, told Reuters Health by…
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