Research in precision immunology is in its early stages. But new insights into cohorts, RA gene expression and infection presented at FOCUS 2017 may benefit future research and patient care…
A Rose by Any Other Name: Why clinicians & patients prefer the term myalgic encephalomyelitis & other updates on chronic fatigue syndrome
A session at the FOCIS 2017 meeting examined the current challenges and understanding of chronic fatigue syndrome, also called myalgic encephalomyelitis, in the hope of stimulating new approaches to deciphering the disease’s mechanistic and immunological underpinnings…
AMP RA/Lupus Network Shares Its Progress
Researchers from the AMP RA/Lupus Network came together in June at the annual FOCIS meeting to share their progress as they perform a systematic molecular deconstruction of human diseases…
Lupus Incidence, Prevalence Differ by Race
NEW YORK (Reuters Health)—Racial and ethnic disparities in systemic lupus erythematosus (SLE) incidence and prevalence are considerable, according to two new studies of data from California and Manhattan. “The most important finding of the population-based California and New York registries is the confirmation of the racial and ethnic disparities of SLE, with the highest incidence…
Undetected Fractures Linked to Back Pain in Older Men
(Reuters Health)—About three in five older men with tiny spinal fractures related to osteoporosis reported new or worsening back pain in a new study. Only about one-quarter of new vertebral fractures are diagnosed by a doctor, the study team writes in their September 7 online report in Journal of Bone and Mineral Research, though the…
Inflammatory Spinal Disorders Common in IBD Patients
NEW YORK (Reuters Health)—Ankylosing spondylitis (AS), axial spondyloarthritis (SpA) and inflammatory back pain are common in inflammatory bowel disease (IBD) patients two decades after IBD diagnosis, according to findings from the IBSEN study1. Doctors should know IBD patients are at risk of inflammatory back problems, and refer them to a rheumatologist when appropriate, Dr. Alvilde Ossum…
Reassuring Data on Cancer Risk with Contemporary RA Drugs
NEW YORK (Reuters Health)—A large Swedish study1 provides reassuring data on the risk of cancer in patients with rheumatoid arthritis (RA) treated with tumor necrosis factor (TNF) inhibitors or with tocilizumab, abatacept or rituximab. Overall, the risk of malignant neoplasms did not differ between patients treated with a first anti-TNF drug; a second anti-TNF drug; tocilizumab,…
Poor Sleep Associated with Higher Risk of Chronic Pain
(Reuters Health)—People who sleep poorly may be more likely to develop a chronic pain condition and have worse physical health, a study from the U.K. suggests. A general decline in both the quantity and quality of hours slept led to a two- to three-fold increase in pain problems over time, researchers found. “Sleep and pain…
TNF Inhibitor Drug Tapering Successful in Some Patients with RA
MADRID—Scores on the Health Assessment Questionnaire for Rheumatoid Arthritis (HAQ) and C-reactive protein (CRP) levels were independent predictors of whether patients could be tapered successfully from a TNF inhibitor after having reached remission of their RA, according to findings presented in a session at the Annual European Congress of Rheumatology. Researchers also developed a composite…
Whole-Body MRI, Ultrasound Imaging May Aid in Early Rheumatic Disease Diagnosis, Treatment
MADRID—Researchers say that whole-body MRI could yield an earlier diagnosis of spondyloarthropathy (SpA) in patients with early inflammatory joint symptoms, according to findings presented in a poster session at the Annual European Congress of Rheumatology (EULAR). The approach could lead to earlier treatment and better outcomes, they say. Investigators at the University of Leeds recruited…
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