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An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

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Conditions

Subcategories:Axial SpondyloarthritisGout and Crystalline ArthritisGuidelinesMyositisOsteoarthritis and Bone DisordersOther Rheumatic ConditionsPain SyndromesPediatric ConditionsPsoriatic ArthritisRheumatoid ArthritisSjögren’s DiseaseSoft Tissue PainSystemic Lupus ErythematosusSystemic SclerosisVasculitis

Complex Treatment: Cancer, Immunotherapy & Rheumatic Disease

Richard Quinn  |  May 6, 2017

Some cancer patients taking immune checkpoint inhibitors experience immune-related adverse events. Laura C. Cappelli, MD, MHS, says rheumatologists are natural partners with oncologists to treat this patient population…

Institute for Clinical Economic Review Final Report on RA Treatments

Mary Beth Nierengarten  |  May 4, 2017

On April 7, 2017, the Institute for Clinical and Economic Review (ICER) published its final report, titled, Targeted Immune Modulators for Rheumatoid Arthritis: Effectiveness & Value.1 The stated objective of the report was to assess the comparative clinical effectiveness of the targeted immune modulators (TIMs) used to treat patients with moderate to severe active rheumatoid…

Treating Uveitis with Adalimumab Improves Quality of Life

Marilynn Larkin  |  May 2, 2017

NEW YORK (Reuters Health)—Treatment of uveitis with adalimumab is linked with “clinically meaningful” differences in quality of life compared with treatment with placebo, new research shows. Dr. John Sheppard of Eastern Virginia Medical School in Norfolk, Va., tells Reuters Health, “Regardless of underlying etiology or lack thereof, uveitis can have a profoundly adverse effect upon…

FDA to Review Immediate-Release Oxycodone; Plus NICE Recommends Secukinumab

Michele B. Kaufman, PharmD, BCGP  |  May 1, 2017

A new formulation of oxycodone in 10 and 15 mg doses is being reviewed by the FDA for treating pain…

MicroRNAs Provide Insight into Bone Metabolism

Lara C. Pullen, PhD  |  May 1, 2017

A recent study examined the functional variants within microRNAs that affect bone metabolism and possibly bone disorders. Researchers found overexpression of microRNAs may contribute to the osteoporotic phenotype, and the gene targets associated with two specific osteoblast-expressed microRNAs may be critical in osteoporosis…

One Stop: Multi-Disciplinary Lupus Clinic Meets Patient Needs

Karen Appold  |  April 28, 2017

Multi-disciplinary care may be a slowly growing trend. One clinic in Ohio is raising the bar for lupus patients, serving as a one-stop center for diagnostic testing, imaging services and physical therapy. The clinic is also able to conduct basic research to advance lupus treatment and tests…

Mindfulness-Based Stress Reduction Only Slightly Improves Low Back Pain

Will Boggs, MD  |  April 26, 2017

(Reuters Health)—Mindfulness-based stress reduction programs (MSBR) appear to improve low back pain only slightly, and only temporarily, a review of previous research suggests. These programs combine meditation while sitting and walking, yoga, focusing attention on different parts of the body and incorporation of mindfulness/awareness into everyday life. Earlier studies found MBSR to be helpful for…

Tofacitinib Treatment May Improve Nail Psoriasis

Rita Buckley  |  April 24, 2017

NEW YORK (Reuters Health)—The oral Janus kinase (JAK) inhibitor tofacitinib appears to improve moderate to severe nail psoriasis, according to a new study. “Nails are hard to treat in psoriasis and we need better treatments,” says Dr. Luis Garza, a dermatologist at Johns Hopkins School of Medicine in Baltimore, who was not involved in the research….

Plasma Complement Activation in Rheumatic Diseases May Accelerate Coronary Artery Disease

Lara C. Pullen, PhD  |  April 24, 2017

A recent study examined the relationship between complement activation and coronary artery disease in patients with rheumatic disease. Researchers found these patients had higher plasma terminal complement complexes and more complement activation in the vascular adventitia, which may accelerate cardiovascular disease and act as a target for new therapies…

NKTR-181 Promising for Chronic Low Back Pain

Michele B. Kaufman, PharmD, BCGP  |  April 21, 2017

NKTR-181, a mu-opioid agonist analgesic, has proved safe and effective for treating chronic low back pain vs. placebo in a recent clinical trial…

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