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Drug Updates

Subcategories:AnalgesicsBiologics/DMARDs

Rheumatologists Air Frustrations with Pharmacy Benefit Managers at Annual Meeting

Larry Beresford  |  January 19, 2018

SAN DIEGO—Pharmacy benefit managers (PBMs) and their impact on drug prices and access to high-cost medications by the patients rheumatologists treat was a major theme at the 2017 ACR/ARHP Annual Meeting Nov. 3–8. In one session, industry experts tried to clarify the role for prior authorizations and drug formulary policies and explored ways to constructively…

Should Patients with Rheumatic Disease Switch from Biologic to Biosimilar?

Susan Bernstein  |  January 19, 2018

SAN DIEGO—Should patients with rheumatic diseases switch from a biologic to its biosimilar? At the 2017 ACR/ARHP Annual Meeting’s Great Debate, held Nov. 5, two rheumatologists argued whether to switch or stay put based on safety, efficacy and potential cost savings. First to the podium to make the case for switching, Jonathan Kay, MD, tweaked…

U.S. Hospital Systems Team Up to Launch Generic Drugmaker

Reuters Staff  |  January 18, 2018

NEW YORK (Reuters)—A group of four hospital systems plans to launch a not-for-profit generic drugmaker aimed at combating shortages and high costs of some generic drugs, which they blame on unscrupulous drug companies that hike prices. Intermountain Healthcare said on Thursday it was working with three other large U.S.-based hospital systems including Ascension, SSM Health…

Changes in Bone Markers Predict Fracture Reduction with Anti-Resorptive Drug

Will Boggs MD  |  January 17, 2018

NEW YORK (Reuters Health)—Treatment-related changes in bone formation markers predict vertebral-fracture reduction with anti-resorptive drug therapy, according to a meta-regression analysis of 14 clinical trials. “These results may be useful for the development of new osteoporosis treatments or when considering new populations or dosing regimens with existing treatments,” Dr. Douglas C. Bauer from the University…

Wal-Mart Launches Program to Safely Dispose of Unused Opioids

Reuters Staff  |  January 17, 2018

NEW YORK (Reuters)—Wal-Mart Stores Inc on Wednesday said it will provide customers filling prescriptions for opioids with a packet of powder that will help them dispose of leftover medication in order to help curb misuse and abuse. The company said patients filling any new class II opioid prescriptions at its pharmacies will receive a free…

Biosimilars: Still Waiting for Promise to Materialize

Larry Beresford  |  January 17, 2018

During the 2017 ACR/ARHP Annual Meeting, advances in biosimilar treatments were abuzz. However, many speakers noted that the presence of biosimilars on the market has not yet resulted in greater access to treatment and lower drug pricing in the U.S…

Skin Exam Advised Before Anti-TNF-Alpha Therapy

Rita Buckley  |  January 16, 2018

NEW YORK (Reuters Health)—Using tumor necrosis factor alpha (TNF-alpha) inhibitors for atypical dermatoses may unmask, or perhaps even worsen, cutaneous lymphoma, according to new research. “Our findings suggest that careful skin examination might be required in all patients prescribed anti-TNF-alpha agents, especially those with atypical presentations of benign skin conditions,” says Dr. Joan Guitart of…

Bimekizumab Improves Joint & Skin Symptoms in PsA Patients

Michele B. Kaufman, PharmD, BCGP  |  January 16, 2018

Preliminary results from an ongoing study show that bimekizumab improves joint and skin symptoms in patients with psoriatic arthritis…

FDA Removes Boxed Warning for Combination Asthma Treatment

Michele B. Kaufman, PharmD, BCGP  |  January 10, 2018

Post-market clinical safety trials have indicated that medications containing both long-acting beta agonists (LABAs) and inhaled corticosteroids (ICSs) do not result in more serious asthma-related outcomes than treatment with ICSs alone…

Biosimilar SB2 May Work as Well as Infliximab for Rheumatoid Arthritis

Lara C. Pullen, PhD  |  January 8, 2018

In a 78-week study examining the interchangeability of infliximab with the biosimilar SB2, the treatments demonstrated long-term efficacy, safety and immunogenicity in patients with rheumatoid arthritis. Across all the study’s treatment groups, patients had similar treatment response rates, and the long-term clinical profile of SB2 was comparable with infliximab…

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