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Research Rheum

Ethics Forum: Unexpected Ethical Issues in Private Practice, Clinical Research

Donah Zack Crawford, MA, Jill Johnson, MD, Neal K. Moskowitz, MD, PhD, & James Udell, MD  |  July 14, 2016

Ethical issues that arise in the average rheumatology practice and in clinical research are often straightforward. The AMA Code of Medical Ethics and the Office Practice and Procedures Manual offer useful information.1 In research, the Protocol and Investigators Agreement spells out who you can enroll and how the trial must be conducted. But still—even when…

Lupus Expert Calls for Better Research, Outcomes of Clinical Trials

Thomas R. Collins  |  July 12, 2016

CHICAGO—A lupus expert recently issued a call for action to improve outcomes of lupus clinical trials, a field that has had so many failed potential therapies that he said it seems to be “cursed.” Richard Furie, MD, chief of rheumatology at Northwell Health in New York, said at the ACR’s 2016 State-of-the-Art Clinical Symposium that…

Conformational Flexibility in HLA-B27 Provides Clues to Development of Ankylosing Spondylitis

Kathy Holliman  |  July 11, 2016

Understanding how human leukocyte antigen (HLA) class I molecule B27 promotes spondyloarthritis has intrigued researchers for four decades. Although the association between the single gene variant HLA-B27—specifically some of its subtypes—with ankylosing spondylitis (AS) is particularly strong, how HLA-B27 directly influences disease development has not yet been clearly explained, although hypotheses continue to be generated….

Rheumatology Research Foundation Awards Nearly 85 Education, Training and Research Grants

From the College  |  July 11, 2016

The Rheumatology Research Foundation recently announced that it has awarded grants to 85 rheumatology trainees and professionals. The recipients, who range from medical students and residents to experienced investigators and rheumatologists, will receive funding for essential education and training, as well as innovative research projects. Their applications, which were submitted last year, were closely examined…

RA Choice: A Tool to Improve Patient Literacy

Arthritis Care & Research  |  July 5, 2016

Doctor-patient communication is critical for successfully treating rheumatoid arthritis. But a majority of RA patients report suboptimal shared decision making, sometimes due to language barriers, lack of time, limited health literacy and other factors. A recent pilot study sought to improve patient understanding and communication by employing an adapted medication guide and decision aid during clinical visits. Use of the tool, RA Choice, resulted in an increase in patient knowledge, and a majority of clinicians found it helpful…

Arthritis Prevalence on the Rise, Creating Challenges for Healthcare System

Arthritis & Rheumatology  |  June 28, 2016

Updated projections suggest that arthritis and arthritis-attributable activity limitation will remain large and growing problems for clinical and public health systems, which must plan and create policies and resources to address these future needs. By 2040, the number of U.S. adults with doctor-diagnosed arthritis is projected to increase 49% to 78.4 million. Can the healthcare system accommodate these projected increases? Not without changes. By 2025, the expected demand for rheumatologists is expected to exceed supply by 2,576 adult and 33 pediatric rheumatologists…

From the Expert: Tips for Research Grant Applications & NIH Funding

Richard Quinn  |  June 24, 2016

For researchers, obtaining a highly sought after NIH grant may seem impossible. But Martin Kriegel, MD, PhD, says collaboration and persistence can help. Here are a few tips to help your next grant application pass muster…

Diagnostic Tests, Tips for Gluten-Induced Celiac Disease

Thomas R. Collins  |  June 13, 2016

CHICAGO—Celiac disease—the gluten-induced illness that can be seen alongside rheumatic diseases—has been seen much more commonly over the past 20 years than it was previously, but the illness can come with questions that are not always straightforward, an expert said at the ACR’s State-of-the-Art Clinical Symposium. The disease, in which the small intestine becomes inflamed…

Treatments for Scleroderma with Gastrointestinal Involvement Address Symptoms

Thomas R. Collins  |  June 13, 2016

CHICAGO—Nine out of 10 scleroderma cases include clinical signs of gastrointestinal (GI) involvement, with severe involvement associated with high mortality rates, but the pathology of this is not very well understood, a GI expert said at the ACR’s State-of-the-Art Clinical Symposium. That has left clinicians with a slate of treatments—anti-reflux, antimicrobials and prokinetics—that address only…

University of Alabama at Birmingham’s Division of Clinical Immunology & Rheumatology Recognized for Excellence

Gretchen Henkel  |  June 13, 2016

An interdisciplinary and collaborative environment is a critical factor for the advancement of basic science and clinical research in the academic environment, says William J. Koopman, MD, former director of the University of Alabama at Birmingham’s (UAB’s) Division of Clinical Immunology and Rheumatology. And in 1977, when he was being recruited by Division Director J….

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