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Research Rheum

Lyme Disease Not Predictor of Long-Term Physical, Mental Health Issues

Lara C. Pullen, PhD  |  May 22, 2015

Lyme disease is often considered a cause of chronic fatigue, pain and other incapacitating symptoms. This assumption stems from analyses of patients who seek retreatment for Lyme disease. However, a new study suggests that Lyme disease is not life altering in the long term for most patients. Specifically, patients with culture-confirmed Lyme disease have similar…

Anti-TNF Agents May Improve Clinical Symptoms of Ankylosing Spondylitis

Lara C. Pullen, PhD  |  May 21, 2015

Ankylosing spondylitis primarily affects the joints and ligaments of the spine, but may also have an impact on other joints. Patients experience pain and stiffness that limit mobility in the back and other affected joints. Symptoms can come and go, last for long periods of time and be severe. Anti-tumor necrosis factor (anti-TNF) drugs are…

Rising Costs of Biologics in the U.S. Suggest Need for Negotiation Ability

Rob Goodier (Reuters Health)  |  May 21, 2015

The costs of some disease-modifying therapies outpace prescription drug inflation, saddling insured patients with thousands of dollars in out-of-pocket payments and delayed or denied coverage, two new studies have shown. Disease-modifying therapies for multiple sclerosis are rising in cost five to seven times faster than inflation and cost more in the United States than in…

Bone Microarchitecture Impaired in Active Celiac Disease

Will Boggs, MD (Reuters Health)  |  May 21, 2015

Bone microarchitecture is impaired in premenopausal women with active celiac disease, a new study from Argentina shows. “This report helps us to understand how bone is affected in celiac disease: increasing bone resorption and thinning trabeculae, even losing some number of them,” Dr. María Belén Zanchetta from Instituto de Diagnóstico e Investigaciones Metabólicas in Buenos…

Progress Made in Search for a Fibromyalgia Biomarker

Lara C. Pullen, PhD  |  May 15, 2015

Fibromyalgia syndrome (FMS), rheumatoid arthritis (RA) and spondyloarthritis (SpA) all exhibit multifaceted manifestations, and many patients exhibit overlapping comorbidities. However, patients with FMS are distinct from others in that they experience widespread pain, fatigue and mood changes, including anxiety and depression. Although its hallmark symptom of pain causes rheumatologists to consider FMS a pain disorder,…

Rheumatology Research Foundation Hits 30-Year Milestone

From the College  |  May 15, 2015

At the 2014 ACR/ARHP Annual Meeting in Boston, the Rheumatology Research Foundation staff sat down with a few ACR and ARHP members to get their take on what the Foundation’s 30th anniversary means to them. We spoke with current and former leaders of the Foundation and the ACR, as well as numerous Foundation award recipients,…

Complement Polymorphism Plays Role in RA Pathology

Lara C. Pullen, PhD  |  April 13, 2015

Study proposes increased active C5a recruits neutrophils to arthritic joints to maintain inflammation

2014 ACR/ARHP Annual Meeting: Macrophage Activation Syndrome

Mary Beth Nierengarten  |  April 1, 2015

The pathogenesis of and new classification criteria for MAS

2014 ACR/ARHP Annual Meeting: Methotrexate Use in Patients with RA

Susan Bernstein  |  April 1, 2015

Review of clinical research on methotrexate therapy, effect on patients’ functionality, tolerability, adverse events

2014 ACR/ARHP Annual Meeting: Super Proteins Eyed in Therapies for Rheumatic Diseases

Susan Bernstein  |  April 1, 2015

Immunoglobulin superfamily of proteins, CTLA-4 and PD-1, may generate treatments for RA, SLE

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