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Search results for: Janus kinase inhibitors

Positive Week 12 Results for Rosnilimab in Patients with RA

Michele B. Kaufman, PharmD, BCGP  |  June 18, 2025

Early study results demonstrate that rosnilimab may be safe and effective for patients with rheumatoid arthritis, reducing the signs and symptoms of RA by week 12 and achieving important primary and secondary study end points.

Filed under:Biologics/DMARDsConditionsDrug UpdatesRheumatoid Arthritis Tagged with:Rheumatoid Arthritis (RA)rosnilimab

FDA Approves Upadacitinib for GCA

Michele B. Kaufman, PharmD, BCGP  |  June 16, 2025

Supported by data in patients with new-onset and relapsing giant cell arteritis (GCA), the FDA approved upadacitinib for the treatment of adults with GCA.

Filed under:Biologics/DMARDsConditionsDrug UpdatesVasculitis Tagged with:FDA approvalGCAgiant cell arteritis (GCA)U.S. Food and Drug Administration (FDA)upadacitinib

Editor's Pick

Large International Study Says Flares Rare After COVID Vaccination

Catherine Kolonko  |  April 3, 2025

‘Patients with rheumatologic diseases are rightfully concerned about the risk of flares after getting their COVID vaccines, especially after holding immune modulators,’ says says Physician Editor Bharat Kumar, MD, MME, FACP, FAAAAI, RhMSUS. ‘A new study is reassuring that flares are rare, even after holding or discontinuing immune modulators.’ The development of a vaccine for…

Filed under:ConditionsResearch Rheum Tagged with:COVID-19Flaresresearch reviewsvaccination

Flares Rare After COVID Vaccination

Catherine Kolonko  |  March 7, 2025

The development of a vaccine for COVID-19 changed the course of the pandemic; however, it also raised questions about whether to withhold or reduce immunosuppressive therapies and other medications for patients with inflammatory, rheumatic and musculoskeletal disease (IRMD), note the authors of a new study published in Annals of the Rheumatic Diseases. An argument for…

Filed under:Clinical Criteria/GuidelinesConditionsGuidanceGuidelinesResearch ReviewsResearch Rheum Tagged with:COVID-19flarevaccination

Precision Medicine Study Examines Blood-Based Immunophenotyping in Patients with RA

Katie Robinson  |  March 6, 2025

For patients with rheumatoid arthritis (RA), analyzing immune cell diversity in peripheral blood revealed five major immunotype groups, each exhibiting a different response to various biologic or targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs). This is according to a 2024 study published in Annals of the Rheumatic Disease that aimed to stratify the patients based on…

Filed under:ConditionsResearch ReviewsResearch RheumRheumatoid Arthritis Tagged with:immunophenotypingphenotypePrecision Medicine

Cancer cells

Cancer & RA Drugs: Are Some Drugs Riskier than Others?

Samantha C. Shapiro, MD  |  February 4, 2025

Sendaydiego et al. asked: Do some DMARDs pose a greater cancer risk than others for patients with RA? Here are insights from the study and its clinical implications.

Filed under:ConditionsDrug UpdatesRheumatoid Arthritis

Top Research in Rheumatoid Arthritis Presented at ACR Convergence 2024

Jeffrey Curtis, MD, MS, MPH  |  December 3, 2024

Why this research is relevant to clinicians today & researchers in the future WASHINGTON, D.C.—The ACR Convergence 2024 meeting in Washington, D.C., reflected the continued advancement of science and practical research in the field of rheumatoid arthritis. Highlights this year centered on new RA treatments and new uses of existing treatments; the use of artificial…

Filed under:ACR ConvergenceConditionsGuidanceMeeting ReportsRheumatoid Arthritis Tagged with:ACR Convergence 2024ACR Convergence 2024 RA

Patients with RA in the Setting of Cardiovascular Disease

Samantha C. Shapiro, MD  |  December 3, 2024

How can we best care for our patients from a joint & cardiovascular perspective? That’s the question Christina Charles-Schoeman, MD, MS, professor of medicine and chief, Division of Rheumatology, University of California Los Angeles Medical Center, Santa Monica, Calif., addressed in a session at ACR Convergence 2024.

Filed under:ACR ConvergenceConditionsGuidanceMeeting ReportsRheumatoid Arthritis Tagged with:ACR Convergence 2024ACR Convergence 2024 RA

Where Are We with RA? Prevention, Treatment & Management Challenges

Samantha C. Shapiro, MD  |  December 3, 2024

In this Review Course at ACR Convergence 2024, Iain McInnes, PhD, FRCP, discussed some of the challenges of RA: Remission is drug maintained, multimorbidity abounds, treatment strategies can be complex, & prevention is not yet possible.

Filed under:ACR ConvergenceConditionsRheumatoid Arthritis Tagged with:ACR Convergence 2024ACR Convergence 2024 RA

Should We Manage Men & Women Differently?

Samantha C. Shapiro, MD  |  November 22, 2024

Experts address how sex differences affect the clinical presentation, diagnosis, response to therapy and experience of illness for patients with PsA.

Filed under:ACR ConvergenceConditionsMeeting ReportsPsoriatic Arthritis Tagged with:ACR Convergence 2024ACR Convergence 2024 PsApatient carePsoriatic ArthritisSex DifferencesWomen

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