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Search results for: Tofacitinib

Can SGLT2 Inhibitors Protect Our SLE Patients?

Samantha C. Shapiro, MD  |  December 4, 2023

SAN DIEGO—At ACR Convergence 2023, Plenary Session 2, April M. Jorge, MD, shared data concerning the potential cardio- and renal-protective benefits of sodium-glucose co-transporter-2 inhibitors in patients with systemic lupus erythematosus and lupus nephritis.

Filed under:ACR ConvergenceConditionsMeeting ReportsSystemic Lupus Erythematosus Tagged with:ACR Convergence 2023Lupus nephritis

Clinical Year in Review: 2023

Samantha C. Shapiro, MD  |  December 4, 2023

SAN DIEGO—At ACR Convergence 2023, Philip Seo, MD, MHS, presented an overview of clinical updates in rheumatology from the past year.

Filed under:ACR ConvergenceBiologics/DMARDsConditionsDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2023ankylosing spondylosisPolymyalgia Rheumatica

What’s New in RA Research?

Jason Liebowitz, MD, FACR  |  November 8, 2023

Dr. Aletaha discussed several studies of interventions in pre-RA, including SAVE, STIVEA, PROMPT, PRAIRI, TREAT EARLIER and STOP-RA.

Filed under:EULAR/OtherMeeting ReportsRheumatoid Arthritis Tagged with:RA Resource CenterRheumatoid Arthritis (RA)

All That Is Old—& New: Treatment Implications for Rheumatoid Arthritis

Jason Liebowitz, MD, FACR  |  November 7, 2023

EULAR 2023 (MILAN)—Over the past several years, a plethora of new treatments for patients with rheumatoid arthritis (RA) has emerged, while older treatments still play a large role in therapy for many patients. At the EULAR 2023 session titled Rheumatoid Arthritis: New Small Molecules and Old DMARDs, several speakers presented abstracts comparing different treatment effects…

Filed under:Meeting ReportsRheumatoid Arthritis Tagged with:EULAR 2023RA Resource CenterRheumatoid Arthritis (RA)

A Dual Inhibitor Treatment for RA?

Michele B. Kaufman, PharmD, BCGP  |  July 17, 2023

TLL-018, a Janus kinase 1/tyrosine kinase 2 inhibitor, proved more effective for treating patients with RA than tofacitinib, according to a study by Zeng et al.

Filed under:Biologics/DMARDsDrug UpdatesMeeting Reports Tagged with:EULAR 2023

JAK Inhibitors vs. TNF Inhibitors: Understanding Infection Risks

Michele B. Kaufman, PharmD, BCGP  |  April 27, 2023

Research from Choi et al. provides insights into the risk of infection in patients with rheumatoid arthritis (RA), comparing patients treated with Janus kinase inhibitors vs. tumor necrosis inhibitors. The most frequent infection was herpes zoster, with patients treated with JAK inhibitors having a significantly greater risk of herpes zoster infection than those treated with TNF inhibitors.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2022InfectionJAK inhibitorsJanus Kinase InhibitorsRheumatoid Arthritis (RA)TNF inhibitorstumor necrosis factor (TNF) inhibitors

Psoriatic Arthritis Drugs at a Glance, 2023

Mary Choy, PharmD, BCGP, FASHP  |  April 21, 2023

Biosimilars have become a therapeutic turning point for many patients who are living with rheumatic illnesses. Psoriatic arthritis (PsA) is a complex, multi-faceted chronic inflammatory musculoskeletal and skin disease where the treatment has changed considerably over the past few years. Psoriatic arthritis has an impact on about 30% of people with psoriasis.1 In 2019, the…

Filed under:ConditionsDrug UpdatesPsoriatic Arthritis Tagged with:PsA Resource CenterPsoriatic Arthritis

Cardiovascular Safety with RA Treatments

Michele B. Kaufman, PharmD, BCGP  |  March 2, 2023

Research by Chicre et al. found that Janus kinase inhibitors may significantly increase the risk of major adverse cardiac events and all-cause death in patients with rheumatoid arthritis (RA) when compared with other RA treatments. This study highlights the need for more comparative safety studies.

Filed under:ConditionsDrug UpdatesRheumatoid Arthritis Tagged with:cardiovascularcardiovascular eventJAK inhibitorJanus Kinase InhibitorsRA Resource CenterRheumatoid Arthritis (RA)TNF inhibitorsTofacitinib

FDA Officials Speak Out: New Approvals & Safety Concerns Discussed

Thomas R. Collins  |  December 13, 2022

PHILADELPHIA—Officials from the U.S. Food & Drug Administration discussed recent drug approvals and drug safety issues at ACR Convergence in November in a session that captured the flurry of activity in the rheumatology sphere at the agency over the past year. Sabiha Khan, MD, clinical reviewer in the Division of Rheumatology and Transplant Medicine at…

Filed under:ACR ConvergenceDrug UpdatesLegislation & AdvocacyMeeting ReportsProfessional Topics Tagged with:ACR Convergence 2022drug approvalsFDA

String of Pearls: Lessons in Rheumatoid Arthritis

Jason Liebowitz, MD, FACR  |  December 6, 2022

PHILADELPHIA—William “Bill” R. Palmer, MD, MACR, was the first board-certified rheumatologist in Omaha, Neb., where he spent his entire 43-year clinical career and established himself as a great clinician, mentor and educator. Although Dr. Palmer passed away from metastatic thyroid cancer in August 2021, his memory lives on through his physician colleagues and at ACR…

Filed under:ACR ConvergenceConditionsMeeting ReportsRheumatoid Arthritis Tagged with:ACR Convergence 2022Rheumatoid arthritisRheumatoid Arthritis (RA)

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