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Search results for: allopurinol

Piclidenoson in Trials for Psoriasis & RA; Plus Duzallo Approved in Europe

Michele B. Kaufman, PharmD, BCGP  |  September 18, 2018

New clinical trials are underway to determine the safety and efficacy of piclidenoson for patients with plaque psoriasis and rheumatoid arthritis…

Filed under:Drug Updates Tagged with:DuzalloEuropeInternationalpiclidenosonPsoriasisRheumatoid Arthritis (RA)

5 Takeaways from the ACR’s Gout Clinical Quality Measures

Carina Stanton  |  August 7, 2018

With electronic clinical quality measures tailored for treating gout patients, physicians and their teams now have tools to measure and improve gout care performance and outcomes…

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:Goutpatient careQuality Measuresurate-lowering therapies

New Study Raises Cardiovascular Questions about Febuxostat for Gout

Lara C. Pullen, PhD  |  April 30, 2018

New research raises questions about the cardiovascular safety of febuxostat for gout patients compared with allopurinol. The study found that although febuxostat was noninferior to allopurinol, febuxostat-treated patients had similar overall rates of major adverse cardiovascular events as allopurinol-treated patients, but had higher rates of all-cause mortality and cardiovascular mortality…

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:AllopurinolcardiovascularFebuxostathyperuricemiarisk

PhuShutter / shutterstock.com

The FDA Approved Several New Rheumatology Drugs in 2017

Larry Beresford  |  March 18, 2018

SAN DIEGO—In a session at the 2017 ACR/ARHP Annual Meeting, Kam Nola, PharmD, MS, professor in the College of Pharmacy and vice chair in the Department of Pharmacy Practice at Lipscomb University in Nashville, Tenn., updated participants on new medications and new indications for rheumatology treatments and safety labeling changes approved by the U.S. Food…

Filed under:Drug UpdatesMeeting Reports Tagged with:abaloparatideACR/ARHP Annual MeetingAllopurinolbelimumabbrodalumabguselkumablesinuradMethotrexatesarilumabtocilizumab

Study Finds Newer Gout Drug Poses Risk to Heart Patients

Gene Emery  |  March 12, 2018

(Reuters Health)—Gout sufferers with major pre-existing heart disease face a higher risk of death if they are treated with the drug febuxostat, a large long-term study has concluded. The risk of death from cardiovascular disease was 34% higher with febuxostat than with allopurinol. When researchers considered deaths from any cause, the risk was 22% higher…

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:AllopurinolCardiovascular diseaseFebuxostatGoutHeart Diseasestroke

New Rheumatology Disease Research & Advice

Thomas R. Collins  |  February 17, 2018

SAN DIEGO—Top researchers gathered for a review course at the start of the 2017 ACR/ARHP Annual Meeting in November to describe new research, their own treatment strategies and new ways of thinking about an array of rheumatic diseases. Here are the highlights: Raynaud’s & Other Digit Problems When a patient walks into your clinic with…

Filed under:Axial SpondyloarthritisMeeting ReportsOsteoarthritis and Bone DisordersRheumatoid ArthritisSystemic SclerosisVasculitis Tagged with:ACR/ARHP Annual Meetingadhesive capsulitisANCAaxial spondyloarthritis (SpA)diabetesDry eyeEthicslung diseasemeniscus surgeryOsteoarthritisRaynaud'sred eyeRheumatoid arthritisscleritisVasculitis

A History of the Science, Treatment of Rheumatologic Illnesses from Gold to Gene Therapy

Simon M. Helfgott, MD  |  December 17, 2017

Mysterious Ways The juxtaposition of the old and the new was readily evident that busy Wednesday morning. My first patient, a 94-year-old gentleman, Hal, arrived with a precise request. His rheumatologist for the past 40 years had just retired, and he was searching for a doctor with expertise in the use of gold sodium aurothioglucose,…

Filed under:ConditionsOpinionResearch RheumRheuminationsSpeak Out Rheum Tagged with:American College of Rheumatology (ACR)American Rheumatism AssociationArthritisautoimmune mediated diseasebioinformaticsC-reactive proteinClinicalcorticosteroid drugsDiagnosisgenomicsHistoryimmune-suppressive therapiesinflammationknowledgemedicalpatient careResearchRheumatic Diseaserheumatologysciencetranslational researchTreatment

European Commission Approves Subcutaneous Belimumab for SLE; FDA Safety Alert for Febuxostat

Michele B. Kaufman, PharmD, BCGP  |  November 29, 2017

Subcutaneous belimumab has been approved in the EU to help treat patients with active autoantibody-positive SLE…

Filed under:ConditionsDrug UpdatesGout and Crystalline Arthritis Tagged with:belimumabcardiovascularEuropean UnionFebuxostatGoutInternationalsystemic lupus erythematosus (SLE)

How to Manage Pain & Treatment in Elderly Patients

Richard Quinn  |  August 25, 2017

Elderly patients have unique requirements with regard to treatment for pain, rheumatic disease and other ailments. Collaboration between rheumatologists, geriatricians and primary care physicians is essential to avoid unnecessary interventions and improve care for this patient population…

Filed under:Practice Support Tagged with:elderlygeriatricgeriatricspatient careTreatment

FDA Approves Duzallo for Hyperuricemia in Patients with Uncontrolled Gout

Reuters Staff  |  August 21, 2017

(Reuters)—Ironwood Pharmaceuticals Inc. said on Monday the U.S. Food and Drug Administration (FDA) approved its oral drug to treat a condition associated with gout. The company’s once-daily drug, Duzallo (lesinurad and allopurinol), was approved to treat hyperuricemia in patients with gout, Ironwood said. Duzallo combines the standard-of-care treatment, allopurinol, with Ironwood’s lesinurad to treat inefficient…

Filed under:ConditionsDrug UpdatesGout and Crystalline Arthritis Tagged with:AllopurinolFDAFood and Drug AdministrationGoutIronwood Pharmaceuticals Inc.lesinurad

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