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Search results for: axial spondyloarthritis

15,000 Patient-Years: Safety Data for Upadacitinib Treatment Across Multiple Rheumatic Conditions

Michele B. Kaufman, PharmD, BCGP  |  October 17, 2024

Burmester et al. characterized the long-term safety profile of upadacitinib treatment across multiple rheumatic diseases.

Filed under:Biologics/DMARDsConditionsDrug UpdatesEULAR/OtherMeeting Reports Tagged with:EULAREULAR 2024Safetyupadacitinib

Measures of Success

Jason Liebowitz, MD, FACR  |  September 24, 2024

Can a treat-to-target strategy achieve better outcomes for patients with spondyloarthritis? Insights from the latest data.

Filed under:Axial SpondyloarthritisConditionsEULAR/OtherGuidanceMeeting Reports Tagged with:APLARAPLAR 2024AS Resource CenterAsia Pacific League of Associations for Rheumatology (APLAR)axial spondyloarthritis (SpA)Diagnosisspondyloarthritis (SpA)Treat-to-Target

Plan Ahead: Clinical Tips for Managing Reproductive Health in Patients with Rheumatic Disease

Jason Liebowitz, MD, FACR  |  September 24, 2024

Dr. May Ching Soh highlighted practical approaches when caring for pregnant patients with rheumatic disease.

Filed under:ConditionsMeeting Reports Tagged with:APLARAPLAR 2024Asia Pacific League of Associations for Rheumatology (APLAR)pregnancypregnancy complicationspregnant women

FDA Approves 2 Upadacitinib Formulations for Children with pJIA & PsA

Michele B. Kaufman, PharmD, BCGP  |  August 13, 2024

Upadacitinib, as a tablet and oral solution, is now FDA approved to treat children age 2 years and older with active polyarticular juvenile idiopathic arthritis or psoriatic arthritis.

Filed under:Biologics/DMARDsConditionsDrug UpdatesPediatric Conditions Tagged with:FDAFDA approvalpJIApolyarticular juvenile idiopathic arthritis (JIA)PsAPsA Resource CenterPsoriatic ArthritisU.S. Food and Drug Administration (FDA)upadacitinib

What’s New in Large Vessel Vasculitis

Philip Seo, MD, MHS  |  August 7, 2024

The large vessel vasculitides were a major focus of the 21st International Vasculitis Workshop held in Barcelona in April. The biennial conference brings together specialists from multiple disciplines, including rheumatology, nephrology and immunology, to discuss cutting-edge vasculitis research. This article reviews important points regarding the pathogenesis, diagnosis and management of both giant cell arteritis and…

Filed under:ConditionsGuidanceResearch RheumVasculitis Tagged with:diverticulitisgastrointestinal perforationGiant Cell Arteritisgiant cell arteritis (GCA)interleukin-17A inhibitorlarge-vessel vasculitisTakayasu arteritis (TAK)Takayasu’s Arteritistocilizumab

Can Reconsidering Our Relationship to Time Help Keep Us Present?

Bharat Kumar, MD, MME, FACP, FAAAAI, RhMSUS  |  February 9, 2024

“I circled 30 minutes … but it feels more like five hours getting ready for work Monday to Friday and only 15 minutes in a hot bath on weekends,” my patient relayed to me. Greg (name changed, obviously) is an ambitious young professional who has axial spondyloarthritis. He’s also a really funny guy with a…

Filed under:OpinionPatient PerspectiveRheuminations

When a JAK Inhibitor Fails

Michele B. Kaufman, PharmD, BCGP  |  January 24, 2024

What Are the Therapeutic Alternatives When a Janus Kinase Inhibitor Fails to Work? SAN DIEGO—Treatment alternatives after Janus kinase (JAK) inhibitor failure in real-life conditions were analyzed and presented at ACR Convergence 2023 by Pablo Francisco Muñoz Martínez, a rheumatologist at the Hospital Universitario y Politécnico La Fe, Sagunto, Spain.1 JAK inhibitors are newer, targeted…

Filed under:ACR ConvergenceBiologics/DMARDsDrug Updates Tagged with:ACR Convergence 2023JAK inhibitorsJanus Kinase Inhibitors

The Heterogeneity of Psoriatic Arthritis

David S. Pisetsky, MD, PhD  |  November 21, 2023

SAN DIEGO—Differences between psoriatic arthritis and rheumatoid arthritis highlight the need for the development of imaging modalities, laboratory tests and other biomarkers that are explored and validated specifically for PsA to advance the goal of personalized or precision medicine. In this article, expert David S. Pisetsky, MD, PhD, explores the top research in psoriatic arthritis presented at ACR Convergence 2023.

Filed under:ACR ConvergenceConditionsMeeting ReportsPsoriatic Arthritis Tagged with:ACR Convergence 2023ACR Convergence 2023 PsAPsA Resource Center

Pearls & Pitfalls in Diagnosing nr-axSpA

Keri Losavio  |  October 19, 2023

This session (12S114) at ACR Convergence 2023 will review the diagnostic approach to nonradiographic axial spondyloarthritis, with an emphasis on the role of imaging and recognition of its mimics. For your review—or a preview if you plan to catch the session on demand—our article will capture the highlights from Lianne Gensler, MD, Mark Hwang, MD,…

Filed under:Uncategorized Tagged with:ACR Convergence 2023ACR Convergence 2023 PsA

The Effect of Upadacitinib on Bone Erosion in Patients with RA

Michele B. Kaufman, PharmD, BCGP  |  May 2, 2023

Ho et al. found that upadacitinib may impede the progression of bone erosion in patients with RA. Additionally, bone scans of patients with limited exposure to conventional synthetic disease-modifying antirheumatic drugs showed bone erosion regression, which may result from upadacitinib’s inhibition of Janus kinase 1.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2022bonebone erosionRheumatoid Arthritis (RA)upadacitinib

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