A recent study found that the perception of experimentally induced pain is closely associated with neurocognitive symptoms, such as attention, memory and executive function, in fibromyalgia patients. Specifically, fibromyalgia patients described low-intensity pressure as more painful than controls did…
New research identifies how education designed to empower self-care and collaboration among providers, patients and family members can help patients with Sjögren’s syndrome manage their daily challenges and take back their lives…
Celiac disease and gluten sensitivity are difficult to diagnose, but they affect multiple systems and are associated with other autoimmune diseases. Lan Chen, MD, PhD, believes better testing and clearer education will be a gamechanger for celiac patients…
Immune checkpoint inhibitors (ICIs) are at the forefront of advances in cancer therapy and have shown promising results for progression-free survival. Checkpoint signaling pathways, such as cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death protein 1 (PD-1), normally regulate the immune response to promote self-tolerance and prevent tissue damage and inflammation. PD-1 is a…
A 36-year-old woman presented at the Johns Hopkins Arthritis Center for a second opinion regarding a diagnosis of psoriatic arthritis (PsA). One year prior to our evaluation, she had developed pain and stiffness in her hands, feet, knees, ankles, elbows and shoulders. She had mild plaque psoriasis of the scalp and base of the neck,…
A recent study found that baricitinib improved symptoms of arthritis and rash in patients with active SLE, while maintaining a safety profile consistent with previous findings…
Rheumatologists can act as advocates for patients and their families in a way that supports targeting vasculitis early. Here’s how…
New research explores the genome-wide epigenetic changes associated with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The results suggest distinct patterns in DNA methylation may become a useful diagnostic marker…
Every single morning—even on weekends—Robert W. Simms, MD, wakes up at 3:45 and is out the door by 4:30 to swim, run or cycle for at least one hour. After weekday workouts, he then heads to his job at Boston University (BU) School of Medicine, where he serves as professor of medicine and rheumatology section…
As if the fatigue, joint pain, etc., were not enough, new research has found many lupus patients must contend with clinical depression as well—something that can have a devastating cascade effect on other areas of their lives. Are adults with childhood-onset lupus at greater risk of depression than lupus patients with onset of disease during…