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University of Nebraska Division of Rheumatology and Immunology Makes Education, Clinical Research Top Priorities

Gretchen Henkel  |  August 13, 2017

When it was created in 1982, the Division of Rheumatology and Immunology at the University of Nebraska Medical Center comprised one-and-a-half rheumatologists: its founder, Lynell W. Klassen, MD, MACR, and Gerald Moore, MD, who later received formal training at the NIH and now serves as senior associate dean for academic affairs. Thirty-five years later, the…

Filed under:ConditionsEducation & TrainingMyositisProfilesResearch Rheum Tagged with:biobanksClinical researchEducationgout and systemic lupus erythematosusImmunologymyositisRheumatoid arthritisrheumatologySclerodermaTrainingtrialsUniversity of Nebraska

Fellows' Forum Case Report: Hemophagocytic Lymphohistiocytosis

Fellows’ Forum Case Report: Hemophagocytic Lymphohistiocytosis

Anita Laloo, MB, BS, MPH, German Pihan, MD, & Robert H. Shmerling, MD  |  August 13, 2017

The patient was a 48-year-old woman who saw her primary care physician for a flu-like illness three months prior to admission. Her symptoms initially improved, but recurred one month later; she was treated symptomatically, and again symptoms resolved. Two months later, she presented to an outside facility’s emergency department with fever to 103ºF, with associated…

Filed under:ConditionsResearch Rheum Tagged with:case reportClinicalDiagnosisFellowsFellows Forumfeverhemophagocytic lymphohistiocytosisimmunodeficiencylymphomamalignancyoutcomepatient careResearchrheumatologysymptoms

Aims Review Committee Helps Rheumatology Researchers Craft Grant Proposals

Elizabeth Hofheinz, MPH, MEd  |  August 13, 2017

There you are, working steadily away on your next manuscript. The ideas are flowing. You’ve hit your stride. Nothing can stop you now—nothing, that is, except a colleague who shows up at your desk with a 20-page grant proposal. “Do you mind?” he asks. Across academia the problem is the same—too few hours in the…

Filed under:Professional TopicsResearch Rheum Tagged with:Aims Review CommitteeFundinggrant writingGrantsproposalResearchrheumatology

Gut Microbe, Prevotella copri, Implicated in RA Pathogenesis

Kathy Holliman  |  August 13, 2017

New research reinforces the hypothesis that the gut microbiome triggers mucosal and systemic immune responses in patients with rheumatoid arthritis. The research, published in Arthritis & Rheumatology May 2017, found that subgroups of patients with RA have differential immunoglobulin G (IgG) or IgA immune reactivity with Prevotella copri, an intestinal microbe that appears to be…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:ACR JournalAmerican College of Rheumatology (ACR)DiagnosisgutmicrobeMicrobiomePathogenesispatient carePrevotella copriRAResearchRheumatic DiseaseRheumatoid arthritisrheumatologistrheumatologyTreatment

Effectiveness of Retinoic Acid, Hydroxychloroquine Examined for Hand OA

Lindsey MacFarlane, MD, MPH  |  August 13, 2017

The Osteoarthritis Research Society International (OARSI) held the 2017 OARSI World Congress in Las Vegas, April 27–30. Below, we report on two of the sessions held. Retinoic Acid & Hand Osteoarthritis Retinoic acid is a vitamin A derivative and hormonal signaling molecule with a role in cartilage and skeletal development. Retinoic acid has complex function,…

Filed under:ConditionsMeeting ReportsOsteoarthritis and Bone DisordersResearch Rheum Tagged with:2017 OARSI World Congresshand osteoarthritisHYDROXYCHLOROQUINEOsteoarthritis Research Society InternationalResearchretinoic acidrheumatologystudiessymptomsTreatment

Fellows’ Forum Case Report: Tophaceous Bullae

Mark Vercel, DO, Kim Reinhart, OMS-3, & Amita Thakkar, MD  |  August 13, 2017

As a manifestation of hyperuricemia, inflammatory bullous lesions have rarely been described in the past century. A more classic presentation of hyperuricemia is acute inflammatory gouty arthritis, characterized by the deposition of monosodium urate crystals. Other complications of chronic untreated hyperuricemia may include polyarticular arthritis, tophus formation and possible chronic destructive lesions of the bone,…

Filed under:Conditions Tagged with:case reportClinicalFellowsFellows ForumoutcomeRheumatic DiseaserheumatologyTophaceous Bullae

Is an Arthritis Vaccine Using Genetically Reprogrammed Stem Cells on the Horizon?

Elizabeth Hofheinz, MPH, MEd  |  August 13, 2017

The words genetically modified are making people run for the hills these days. Not so when it comes to arthritis care, however. In the lab of one pioneering researcher, genetic engineering is catapulting arthritis treatment years ahead. Farshid Guilak, PhD, is a professor in the Department of Orthopaedic Surgery at Washington University, St. Louis, and…

Filed under:ConditionsResearch Rheum Tagged with:anti-inflammatory drugArthritisgeneticinflammationResearchRheumatic Diseaserheumatologystem cellvaccine

Refocus Your Practice with Invigorating Sessions at 2017 ACR/ARHP Annual Meeting

From the College  |  August 13, 2017

The landscape of practice management and coding methodologies continues to be challenging in the current healthcare environment, and rheumatology practices must maintain focus on managing an effective and efficient practice. Join us at the 2017 ACR/ARHP Annual Meeting, Nov. 3–8 in San Diego, and gain knowledge and understanding of best practices in an ever-changing environment…

Filed under:Career DevelopmentFrom the CollegePractice SupportProfessional Topics Tagged with:2017 ACR/ARHP Annual MeetingAuditsBillingCareerCodingCommittee on Rheumatologic Care (CORC)EducationphysicianPractice ManagementReimbursementrheumatologistrheumatologySan DiegoTraining

Novel Bone Drug Promising in Postmenopausal Osteoporosis

Reuters Staff  |  August 7, 2017

NEW YORK (Reuters Health)—The investigational drug romosozumab led to gains in hip bone mineral density (BMD) that were not seen with teriparatide in older women with osteoporosis transitioning from bisphosphonate therapy in the STRUCTURE study. Amgen’s romosozumab is a monoclonal antibody that inhibits sclerosin, a negative regulator of bone formation. In addition to stimulating bone…

Filed under:Biologics/DMARDsConditionsDrug UpdatesOsteoarthritis and Bone Disorders Tagged with:bone mineral density (BMD)Osteoporosisosteoporosis treatmentspostmenopauseromosozumab

2017 Update of Treat-to-Target Recommendations for Axial & Peripheral SpA & PsA

Michele B. Kaufman, PharmD, BCGP  |  August 7, 2017

An international task force has updated recommendations for axial and peripheral spondyloarthritis, and psoriatic arthritis, which include treat-to-target recommendations…

Filed under:Axial SpondyloarthritisConditions Tagged with:axial spondyloarthritis (SpA)Guidelinesperipheral spondyloarthritisrecommendationstarget

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