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Route of Iron Replacement Doesn’t Impact IBD Activity, Quality of Life

Laura Newman  |  February 20, 2016

NEW YORK (Reuters Health)—The route of iron replacement therapy alters the gut microbiome and metabolomics in patients with inflammatory bowel disease (IBD), but the route is unrelated to disease activity and quality of life, according to a new study. “Crohn’s disease patients are extremely fragile to disturbances and one might speculate about consequences in long-term…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:Crohn's diseasegut microbiomeinflammatory bowel diseaseIron Replacement TherapyMicrobiome

Pfizer Unit to Pay $784.6 Million in Medicaid Rebate Settlement

Reuters Staff  |  February 19, 2016

(Reuters)—Pfizer Inc. said its Wyeth unit has agreed to pay $784.6 million to settle cases related to the calculation of Medicaid rebates for a gastric drug between 2001 and 2006. The claims alleged that Wyeth’s calculation of rebates for its proton pump inhibitor Protonix (pantoprazole) violated the Federal Civil False Claims Act and other laws…

Filed under:Drug UpdatesLegal Updates Tagged with:lawsuitLegalMedicaidPfizer Inc.

Rheumatologist, Pain Physician Collaboration Vital for Better Pain Control

Vanessa Caceres  |  February 17, 2016

Chronic pain can be one of the biggest challenges that patients and their physicians face. Rheumatology patients are no stranger to pain, and when pain goes beyond the scope of what rheumatologists can treat, collaboration with a pain specialist is common. “I refer patients to pain management when there is no underlying inflammatory condition, usual…

Filed under:Practice SupportQuality Assurance/Improvement Tagged with:PainPain Managementpain specialistpatient carerheumatologistTreatment

What Listening to Lungs Might Teach About Rheumatic Disease

Simon M. Helfgott, MD  |  February 17, 2016

One of your first clinical assignments as a medical student was likely to have been the lung exam. Its key descriptors may still resonate in your mind: inspection, palpation, percussion and auscul­tation. Proudly parading down the hospital corridors, your newly purchased stethoscope snugly tucked inside your lab coat pocket, you carefully place its cold metal…

Filed under:ConditionsOpinionRheuminationsSpeak Out Rheum Tagged with:examlungspatient carePulmonaryRheumatic Diseaserheumatologist

APS: What Rheumatologists Should Know about Hughes Syndrome

Graham R.V. Hughes, MD, FRCP  |  February 17, 2016

The problem that dogs the work of all of those treating patients with antiphospholipid syndrome (APS) is the apparent lack of knowledge of the syndrome, both by the general public, as well as by swaths of the medical fraternity. Perhaps it was ever thus—a syndrome less than 40 years old could be described as new,…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:Antiphospholipid Antibody Syndrome (APS)brainClinicalDiagnosisHughes Syndromejointpatient carepregnancyrheumatologiststrokesymptomthrombosis

Case Study in Dermatology: Tender Papules on Elbows, Hands in RA

Drew Kurtzman, MD, & Timothy McCalmont, MD, with Ruth Ann Vleugels, MD, MPH, & Joseph F. Merola, MD, MMSc  |  February 17, 2016

The Case A 41-year-old woman was referred to the dermatology clinic for a three-month history of tender lesions on her elbows and around the joints of her hands. Her medical history was notable for seropositive, non-erosive rheumatoid arthritis (RA), which was being treated with 5 mg pred­nisone daily, 10 mg methotrexate weekly by mouth, 200…

Filed under:ConditionsRheumatoid Arthritis Tagged with:case reportClinicalDermatologyDiagnosispapulespatient careRheumatoid arthritisrheumatologyTreatment

2015 ACR/ARHP Annual Meeting: Next Generation Sequencing and Disease Mechanisms

Mary Beth Nierengarten  |  February 17, 2016

SAN FRANCISCO—By harnessing the power of next generation sequencing strategies and combining them with clever statistical strategies and tools, investigators are striving to define causal pathways of and mechanisms underlying complex diseases, such as rheumatoid arthritis, according to Soumya Raychaudhuri, MD, PhD, associate professor, Harvard Medical School, Brigham and Women’s Hospital, Boston, during a session…

Filed under:ConditionsMeeting ReportsResearch RheumTechnology Tagged with:2015 ACR/ARHP Annual MeetingAmerican College of Rheumatology (ACR)geneticnext generation sequencingpathwaysResearchvariant

FDA Update: Infliximab Biosimilar Garners Support & Fibromyalgia Drug Receives Fast Track

Michele B. Kaufman, PharmD, BCGP  |  February 17, 2016

Recently, an FDA committee announced support for the approval of CT-P13, an infliximab biosimilar. The FDA has also fast tracked the development of a fibromyalgia treatment designed for multiple symptoms…

Filed under:Biologics/DMARDsConditionsDrug UpdatesPain Syndromes Tagged with:drug developmentFDAFibromyalgiaFood and Drug Administrationinfliximab

Rheumatology Case Report: Chondromyxoid Fibroma of the Sternum

Rajaie Namas, MD, Reshma Khan, MD, & Bernard Rubin, DO  |  February 16, 2016

A 47-year-old Caucasian woman presented to the rheumatology clinic with a one-year history of pain and swelling involving the wrists, hands, ankles and feet that progressively worsened. Her symptoms included generalized fatigue, morning stiffness in the hands and lower back lasting more than an hour, Raynaud’s phenomena (triphasic), photosensitivity, tightening of the skin of the…

Filed under:ConditionsSystemic Sclerosis Tagged with:Autoimmune diseasechondromyxoid fibromaClinicalDiagnosisoutcomepatient carerheumatologyScleroderma

Blogging Basics Rheumatologists Should Know

Karen Appold  |  February 16, 2016

To blog or not to blog? As a rheumatologist, you may have pondered this question. Perhaps getting some insight from rheumatologists who already blog and a professional blog writer may help you find the answer. Obviously, if you devoted time to blogging you would want it to be beneficial. For Paul Sufka, MD, rheumatologist, HealthPartners,…

Filed under:Professional TopicsTechnology Tagged with:BlogsGuidelinesonlinephysicianSocial MediaTechnologytips

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