Data from a small study show that severe methotrexate toxicity in patients who are 70 years of age and older and have rheumatic disease may be associated with poor renal function and the use of diuretic treatments.


Data from a small study show that severe methotrexate toxicity in patients who are 70 years of age and older and have rheumatic disease may be associated with poor renal function and the use of diuretic treatments.

A study from Amigues et al. found that bisphosphonate-associated osteonecrosis of the jaw is rare in patients with osteoporosis and may occur more often in patients treated with injectable zoledronic acid than in those treated with the oral bisphosphonates.

The FDA is investigating the risk of severe hypocalcemia with serious outcomes, such as hospitalization and death, in patients on dialysis taking denosumab.

PHILADELPHIA—The term pseudogout has been a source of confusion among rheumatologists, especially as our understanding of calcium pyrophosphate crystal deposition (CPPD) disease has become more nuanced. This condition has many complex and interesting facets that warrant closer investigation. An ACR Convergence 2022 session sought to update the audience on the progress to date in developing…

PHILADELPHIA—Ever since the seminal work of C. Lockard Conley, MD, in 1952 of the discovery of the lupus anticoagulant, antiphospholipid syndrome (APS) has been of great interest to rheumatologists, hematologists and many others. At ACR Convergence 2022, the session titled Draft ACR/EULAR Antiphospholipid Syndrome Classification Criteria sought to summarize the rigorous process that went into…

Lupus Research Alliance Inaugurates Diversity Awards The Lupus Research Alliance (LRA) inaugurated two new award mechanisms this past summer with the goal of alleviating the racial disparities prevalent in both autoimmune diseases and the biomedical research community. Three notable early career scientists from under-represented groups received the Diversity in Lupus Research Career Development Awards, and…

Patrice Fusillo |
Recognition as an ACR Master is one of the highest honors the College bestows. The designation of Master is conferred on ACR members, age 65 or older by Oct. 1 of the year in which they are nominated, who have made outstanding contributions to the ACR and the field of rheumatology through scholarly achievement and/or…

Patrice Fusillo |
During ACR Convergence 2022 in early November, the ACR honored a group of individuals who have made significant contributions to rheumatology research, education and patient care by announcing the recipients of the ACR’s 2022 Awards of Distinction, as well as the 2022 ACR Masters, recognized for their contributions to the field. See the November issue…

The Rheumatologist (TR) premiered in 2006, with its first full year of publication in 2007. In the 15 years since, it has sought to provide clinicians, researchers and healthcare providers with the most stimulating and educational content found in the field of rheumatology. The responsibility for achieving this mission has been borne by just three…

Lauren Harper, MD |
Tongue Twister 12-year-old girl who had been diagnosed with Moebius syndrome a year earlier presented for evaluation of progressive tongue hemiatrophy that was causing her difficulty with eating and speaking. Magnetic resonance imaging (MRI) of the brain demonstrated tongue hemiatrophy without involvement of the hypoglossal nerve. A tongue biopsy showed atrophy of skeletal muscle, variably…