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Search results for: methotrexate

Not All Rheumatoid Factor-Positive Tests Mean RA

Francis Essien, DO, & Matthew B. Carroll, MD, FACP, FACR  |  April 15, 2020

Angioimmunoblastic T cell lymphoma (AITL) is an aggressive, peripheral T cell, non-Hodgkin’s lymphoma with an incidence of 0.05 cases per 100,000 person-years in the U.S., and it typically manifests in adults older than 60 years.1,2 AITL was previously known as angio­immunoblastic lymphadenopathy with dysproteinemia, immunoblastic lympha­denopathy or lymphogranulomatosis X, due to the hypothesis that the…

Filed under:ConditionsRheumatoid Arthritis Tagged with:Cancercase reportRheumatoid Factor

2 Patients on Different DMARDs Experience Different COVID-19 Disease Courses

Luis A. Marcos, MD, MPH, Saika Sharmeen, DO, Jaime Gonzalez, MD, Qingping Yao, MD, PhD, Bettina Fries, MD, & Jack Fuhrer, MD  |  April 13, 2020

In March 2020, an elderly married couple living on Long Island, N.Y., presented to our emergency department with symptoms suspicious for COVID-19 infection. The wife, a-76-year-old woman, presented with complaints of subjective fevers, minimal dry cough and headaches of one-week duration. She denied having any chills, rhinorrhea, diarrhea, abdominal pain or shortness of breath. Two…

Filed under:Conditions Tagged with:COVID-19

No Evidence to Support Biologic Switching Guidelines for JIA

Marilynn Larkin  |  April 1, 2020

NEW YORK (Reuters Health)—For young people with juvenile idiopathic arthritis (JIA) who don’t achieve disease control, switching to a different class of biologic is unlikely to be beneficial, researchers say. The observational study yielded no evidence to support or refute the 2015 National Health Service England guidelines, which recommend switching most patients to a second…

Filed under:ConditionsOther Rheumatic ConditionsPediatric Conditions Tagged with:BiologicsJIAjuvenile idiopathic arthritis (JIA)Pediatric

Pediatric Cases Require Special Considerations & Aggressive Treatment Plans

Thomas R. Collins  |  March 12, 2020

ATLANTA—Managing pediatric patients with rheumatic disease involves special considerations, such as developmental concerns and physiological traits that may affect dosing of medications, according to two experts. During a session at the 2019 ACR/ARP Annual Meeting, Courtney Kremer, ARNP, a pediatric nurse practitioner at the University of Iowa Stead Family Children’s Hospital, Iowa City, and Jessica…

Filed under:Biologics/DMARDsConditionsMeeting ReportsPediatric Conditions Tagged with:2019 ACR/ARP Annual Meetingjuvenile idiopathic arthritis (JIA)

Clinicians Discuss Current & Future Rheumatoid Arthritis Approaches

Mike Fillon  |  March 12, 2020

ATLANTA—When it comes to treating rheumatoid arthritis (RA) patients, most clinicians agree: One size does not fit all. Many treatment options exist, and seldom is there 100% consensus on what the first course of action or general approach should be. In the face of such variability, four clinicians took the stage at the 2019 ACR/ARP…

Filed under:Biologics/DMARDsConditionsMeeting ReportsRheumatoid Arthritis Tagged with:2019 ACR/ARP Annual MeetingCancerPrecision Medicine

FDA Update: New Drug Approvals, New & Expanded Indications, & More

Susan Bernstein  |  March 12, 2020

ATLANTA—New drug approvals, new and expanded drug indications, and important safety and other updates relevant for rheumatologists were presented by three physicians from the U.S. Food & Drug Administration (FDA) on Nov. 11 at the 2019 ACR/ARP Annual Meeting. New JAK Inhibitor Approved for RA On Aug. 16, 2019, the FDA approved upadacitinib (Rinvoq), an…

Filed under:Biologics/DMARDsDrug UpdatesMeeting Reports Tagged with:2019 ACR/ARP Annual MeetingapremilastCertolizumab PegolFebuxostatixekizumabJAK inhibitorsnintedanibrituximabU.S. Food and Drug Administration (FDA)upadacitinib

The ACR Introduces a New Reproductive Health Guideline

Susan Bernstein  |  March 12, 2020

Reproductive health can be a concern for patients with rheumatic diseases, and practitioners in both rheumatology and obstetrics/gynecology often work closely together. The 2020 ACR Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases, new clinical recommendations developed by an ACR-convened group for pregnant women, post-menopausal women, lactating women, and women and…

Filed under:Clinical Criteria/GuidelinesConditions Tagged with:contraceptivepregnancyreproductive health

Risankizumab & Apremilast Come to Market in Canada

Michele B. Kaufman, PharmD, BCGP  |  March 9, 2020

In Canada, five provinces will now reimburse patients with plaque psoriasis who use risankizumab. Also, Canada Health has approved apremilast for treating adults with plaque psoriasis and psoriatic arthritis…

Filed under:Drug Updates Tagged with:apremilastCanadaplaque psoriasisPsoriatic Arthritisrisankizumab

Thoughtful Pediatric Care: Pediatric Cases Require Special Considerations & Aggressive Treatment Plans

Thomas R. Collins  |  March 9, 2020

In Canada, five provinces will now reimburse patients with plaque psoriasis who use risankizumab. Also, Canada Health has approved apremilast for treating adults with plaque psoriasis and psoriatic arthritis…

Filed under:Conditions Tagged with:2019 ACR/ARP Annual Meetingpediatric arthritisPediatric RheumatologyPediatrics

The ACR Introduces New Reproductive Health Guideline

Susan Bernstein  |  March 4, 2020

The evidence-based guideline includes contraceptive recommendations and suggestions for rheumatologists co-managing patients with obstetrician-gynecologists and other specialists.

Filed under:Clinical Criteria/Guidelines Tagged with:Clinical GuidelinesEliza ChakravartyLisa R. SammaritanoMDMSreproductive health

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