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Search results for: methotrexate

Incarcerated Individuals with Rheumatic Conditions

Katherine Terracina, MD, & Prajakta P. Masurkar, PhD  |  June 8, 2025

In addition to the impediments to consistent, high-quality care suffered by all incarcerated individuals, incarcerated patients with rheumatic disease face challenges specific to the treatment, management & monitoring of rheumatic conditions.

Filed under:EthicsGuidance Tagged with:Chronic disease managementethical considerationsEthics Forumhealth disparitieshealthcare policymedication accesspatient advocacyprison healthcaretelemedicine

New Analysis Reveals More Potential Contributors to Takayasu Arteritis

Bryn Nelson, PhD  |  June 8, 2025

Recent research led to development of a cumulative genetic risk score for Takayasu arteritis, identifying differing susceptibility between groups with different genetic ancestries.

Filed under:ConditionsResearch ReviewsResearch RheumVasculitis Tagged with:genetic susceptibilitygeneticsHLA-B*52large-vessel vasculitispatient communicationphysician-patient communicationPrecision MedicineTakayasu arteritistherapeutic targets

Reactive Arthritis: Chronic or Self-Limiting?

Michael J. Cammarata, MD  |  June 8, 2025

Reactive arthritis has proved to be a diagnostic & therapeutic challenge due to its diverse presentations.

Filed under:Axial SpondyloarthritisConditions Tagged with:biologic DMARDsdisease managementextra-articular manifestationsGlucocorticoidsHLA-B27infectious etiologymusculoskeletal manifestationsNSAIDsReactive arthritisspondyloarthritissulfasalazine

How to Recognize Inborn Errors of Immunity

Vanessa Caceres  |  May 13, 2025

Inborn errors of immunity may not always be easy to recognize, but rheumatologists should look out for them. Dr. Bharat Kumar shares his insights.

Filed under:ConditionsOther Rheumatic Conditions Tagged with:ACR on Airimmune deficiencyinborn errors of immunitypatient carepodcast

Abatacept Shows Promise for Some Myositis Patients

Deborah Levenson  |  May 12, 2025

Injected abatacept may be a worthwhile treatment for certain patients with idiopathic inflammatory myositis (IIM), according to recent research.1 Patients with the rare autoimmune conditions involving inflammation of muscle (myositis) and other organ systems suffer widespread organ dysfunction, increased morbidity, physical disabilities and early death. Symptoms vary by subtype. For example, dermatomyositis (DM) involves muscle…

Filed under:Biologics/DMARDsConditionsDrug UpdatesMyositisResearch ReviewsResearch Rheum Tagged with:abataceptAC&Ridiopathic inflammatory myositis

Nature vs. Nurture & Their Roles in Autoimmunity

Bharat Kumar, MD, MME, FACP, FAAAAI, RhMSUS  |  May 12, 2025

They looked exactly alike—tall, slightly scruffy gentlemen with denim overalls lightly stained with dirt and oil, with dusty trucker hats to match. The only difference was that one wore a red checkered shirt and the other wore a green one. Yet these similarities were deceptive. The one closest to me was the patient, the one…

Filed under:OpinionRheuminations Tagged with:DNAepigeneticsgenetic riskgenetics

Cilnidipine Receives Orphan Drug Status to Treat Systemic Sclerosis

Michele B. Kaufman, PharmD, BCGP  |  May 9, 2025

Based on research showing improved signs and symptoms of systemic sclerosis in patients taking cilnidipine vs. placebo, the FDA granted orphan drug designation for the agent.

Filed under:Biologics/DMARDsConditionsDrug UpdatesSystemic Sclerosis Tagged with:AISA-021cilnidipineFDASScsystemic sclerosis (SSc)U.S. Food and Drug Administration (FDA)

Trends in the Use of DMARDs for Patients with JIA

Arthritis & Rheumatology  |  April 8, 2025

Yalamanchili et al. describe how trends in disease-modifying anti-rheumatic drug (DMARD) use have evolved for insured, U.S. patients with juvenile idiopathic arthritis. Overall, the study found that from 2000 to 2022 in this patient population the use of biologic and targeted synthetic DMARDs rose, while the use of conventional synthetic DMARDs declined.

Filed under:Biologics/DMARDsConditionsDrug UpdatesPediatric Conditions Tagged with:adalimumabDisease-modifying antirheumatic drugs (DMARDs)JIAjuvenile idiopathic arthritis (JIA)prescribingtrends

Editor's Pick

Large International Study Says Flares Rare After COVID Vaccination

Catherine Kolonko  |  April 3, 2025

‘Patients with rheumatologic diseases are rightfully concerned about the risk of flares after getting their COVID vaccines, especially after holding immune modulators,’ says says Physician Editor Bharat Kumar, MD, MME, FACP, FAAAAI, RhMSUS. ‘A new study is reassuring that flares are rare, even after holding or discontinuing immune modulators.’ The development of a vaccine for…

Filed under:ConditionsResearch Rheum Tagged with:COVID-19Flaresresearch reviewsvaccination

Flares Rare After COVID Vaccination

Catherine Kolonko  |  March 7, 2025

The development of a vaccine for COVID-19 changed the course of the pandemic; however, it also raised questions about whether to withhold or reduce immunosuppressive therapies and other medications for patients with inflammatory, rheumatic and musculoskeletal disease (IRMD), note the authors of a new study published in Annals of the Rheumatic Diseases. An argument for…

Filed under:Clinical Criteria/GuidelinesConditionsGuidanceGuidelinesResearch ReviewsResearch Rheum Tagged with:COVID-19flarevaccination

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