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Search results for: secukinumab

Secukinumab Receives 2 New Approvals: PsA & AS

Michele B. Kaufman, PharmD, BCGP  |  January 20, 2016

The FDA approved secukinumab (Cosentyx) this past week for the treatment of adults with active ankylosing spondylitis and active psoriatic arthritis. These two new approvals are based on the safety and efficacy outcomes from four placebo-controlled Phase 3 trials in more than 1,500 adults with AS or PsA…

Filed under:Biologics/DMARDsDrug Updates

Phase 3 Trials: Secukinumab for Psoriatic Arthritis & DA-DKP for OA

Michele B. Kaufman, PharmD, BCGP  |  October 14, 2015

In a global Phase 3 trial, subcutaneous secukinumab proved safe and effective in patients with psoriatic arthritis. Also, a version of aspartyl-alanyl diketopiperazine, a biologic for knee OA, has entered Phase 3 trials…

Filed under:Biologics/DMARDsConditionsDrug UpdatesOsteoarthritis and Bone DisordersOther Rheumatic Conditions Tagged with:analgesicKnee Osteoarthritis (OA)PainPsoriatic Arthritissecukinumab

Secukinumab Effective for Psoriatic Arthritis

Lara C. Pullen, PhD  |  October 12, 2015

A Phase 3 study found secukinumab may be an effective alternative to anti-TNF therapies for treating psoriatic arthritis, suggesting interleukin 17A may play a role in the disease…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:Anti-TNFanti-TNF agentPsoriatic Arthritissecukinumab

Secukinumab Effective for Treating Psoriatic Arthritis

Reuters Staff  |  July 15, 2015

NEW YORK (Reuters Health)—The anti-interleukin-17A monoclonal antibody secukinumab improves signs and symptoms in patients with psoriatic arthritis, according to results from Novartis’ FUTURE 2 trial. In earlier studies, secukinumab has demonstrated superior effectiveness to placebo and etanercept in improving the signs and symptoms of psoriasis. Dr. Iain B. McInnes from the University of Glasgow in…

Filed under:Biologics/DMARDsConditionsDrug UpdatesOther Rheumatic ConditionsPsoriatic Arthritis Tagged with:Biologics & BiosimilarsInterleukinPsoriatic Arthritissecukinumab

Hydrocodone Bitartrate, Secukinumab, Varenicline Updates, Trials, Approvals

Michele B. Kaufman, PharmD, BCGP  |  December 1, 2014

Plus, rheumatology drug news, safety updates

Filed under:AnalgesicsAxial SpondyloarthritisConditionsDrug UpdatesResearch RheumRheumatoid Arthritis Tagged with:Ankylosing SpondylitisApprovalsdrugFDAhydrocodone bitartrateKaufmanlabsPainResearchRheumatoid arthritisrheumatologysecukinumabvarenicline

Trends in the Use of DMARDs for Patients with JIA

Arthritis & Rheumatology  |  April 8, 2025

Yalamanchili et al. describe how trends in disease-modifying anti-rheumatic drug (DMARD) use have evolved for insured, U.S. patients with juvenile idiopathic arthritis. Overall, the study found that from 2000 to 2022 in this patient population the use of biologic and targeted synthetic DMARDs rose, while the use of conventional synthetic DMARDs declined.

Filed under:Biologics/DMARDsConditionsDrug UpdatesPediatric Conditions Tagged with:adalimumabDisease-modifying antirheumatic drugs (DMARDs)JIAjuvenile idiopathic arthritis (JIA)prescribingtrends

The Management of Psoriatic Arthritis: A Review

Samantha C. Shapiro, MD  |  November 17, 2024

WASHINGTON, D.C.—As of November 2024, there are 16 biologic disease-modifying anti-rheumatic drugs (bDMARDs) that are FDA approved for the treatment of psoriatic arthritis (PsA). Incredible news, right? But as my fellowship program director used to say, “There’s no free lunch.” This buffet of options is excellent for our patients, but poses challenges to the practicing…

Filed under:ACR ConvergenceConditionsGuidanceMeeting ReportsPsoriatic Arthritis Tagged with:ACR Convergence 2024ACR Convergence 2024 PsA

Updates from the ACR Insurance Subcommittee

From the College  |  November 12, 2024

The ACR Insurance Subcommittee (ISC) of the Committee on Rheumatologic Care has been hard at work, advocating to payers on behalf of the ACR and its members. Following is an update on some of the work this group has been doing to help address concerns about reimbursement and administrative burden, while ensuring continued access to…

Filed under:Uncategorized

Plan Ahead: Clinical Tips for Managing Reproductive Health in Patients with Rheumatic Disease

Jason Liebowitz, MD, FACR  |  September 24, 2024

Dr. May Ching Soh highlighted practical approaches when caring for pregnant patients with rheumatic disease.

Filed under:ConditionsMeeting Reports Tagged with:APLARAPLAR 2024Asia Pacific League of Associations for Rheumatology (APLAR)pregnancypregnancy complicationspregnant women

What’s New in Large Vessel Vasculitis

Philip Seo, MD, MHS  |  August 7, 2024

The large vessel vasculitides were a major focus of the 21st International Vasculitis Workshop held in Barcelona in April. The biennial conference brings together specialists from multiple disciplines, including rheumatology, nephrology and immunology, to discuss cutting-edge vasculitis research. This article reviews important points regarding the pathogenesis, diagnosis and management of both giant cell arteritis and…

Filed under:ConditionsGuidanceResearch ReviewsResearch RheumVasculitis Tagged with:diverticulitisgastrointestinal perforationGiant Cell Arteritisgiant cell arteritis (GCA)interleukin-17A inhibitorlarge-vessel vasculitisTakayasu arteritis (TAK)Takayasu’s Arteritistocilizumab

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