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Articles tagged with "autoreactive B cells"

The Role of Autoreactive B Cells in Rheumatoid Arthritis

Catherine Kolonko  |  September 17, 2019

The body uses B cells to produce antibodies that can fight off infection by invading antigens and bacteria. But in rheumatoid arthritis (RA), the immune system produces autoantibodies that work against the body’s proteins to attack joint tissues. Researchers believe this process is helped along by autoreactive B cells that live in bone matter and…

Characterization of Autoreactive B Cells in Patients with SLE & RA

Lara C. Pullen, PhD  |  May 6, 2019

Antibody-secreting cells are important for the pathophysiology of SLE and RA, but researchers have been unable to determine how these cells are activated. A new technique is able to distinguish between naïve autoreactive B cells and established antibody secreting cells…

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