Although initially given as replacement therapy for patients with primary and secondary immunodeficiency states, intravenous immunoglobulin (IVIg) has proven to be effective in the treatment of various autoimmune and inflammatory disorders. This success has led to a dramatic increase in the use of IVIg, with its use as an antiinflammatory agent now vastly surpassing its use in the treatment of immunodeficiencies. Even so, the basis for the antiinflammatory activity of IVIg remains unclear.
Where Will Kinase Inhibitors Fit into the RA Treatment Mix?
Presenters at “Looking Ahead to Kinase Inhibition in Rheumatoid Arthritis,” a session here at the 2011 ACR/ARHP Annual Scientific Meeting, delved into some of the big questions that rheumatology faces with kinase inhibitor use.
Information on New Drug Approvals and Medication Safety
Rheumatology-related drug safety, approvals, and what’s in the pipeline.
A Patient’s Perspective on RA
I was diagnosed in April 2010, at 44 years old, with seropositive RA; the disease rapidly turned my life upside down.
A Short History of Rheumatoid Arthritis Therapeutics
Or, why I chose to become a rheumatologist
Drug Updates: Apremilast, Belimumab, and More
Information on new approvals and medication safety
A&R Abstracts: Methotrexate
For further reading
Old Drugs Can Learn New Tricks
Methotrexate and its mechanism of action
Letters
Feedback from our readers
Phoning It In
The missed message on methotrexate