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Articles tagged with "myeloid cells"

Dana Robochek / shutterstock.com

VEXAS: A Newly Identified & Vexing Myeloid-Driven Inflammation

Bryn Nelson, PhD  |  December 14, 2020

A large, international team of rheumatologists, geneticists, hematologists and other researchers has discovered a severe inflammatory syndrome linked to an acquired genetic mutation in the bone marrow of older men. The X-linked syndrome, they found, is caused by a somatic mutation in myeloid stem cells that hobbles the master regulator of a pathway tasked with…

Alterations in Macrophage Activation May Signal a Lupus Flare

Lara C. Pullen, PhD  |  February 11, 2019

New data suggest myeloid cells in SLE patients skew B and T cell activation status toward the M1 proinflammatory phenotype, thereby directing SLE flares and remission…

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