Recent research investigated the progression and characteristics of Sjögren’s syndrome using mice engineered to lack special genome organizing AT-rich sequence binding protein-1 (SATB1). These mice proved to be a novel model for Sjögren’s syndrome and revealed T cell-dominant immune cell infiltration of the salivary glands. Over time, the frequency of B cells gradually increased, as well as the levels of anti-SSA and anti-SSB antibodies…
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