Systemic sclerosis (SSc) is a multi-system connective tissue disease in which skin and internal organ fibrosis are associated with an obliterative micro-vasculopathy and a degree of inflammation.1 Patients often report it takes one to three years from the appearance of the first signs and symptoms before they receive a diagnosis. The signs and symptoms of…
![Light micrograph of a vascular lesion (center) caused by systemic sclerosis.](https://www.the-rheumatologist.org/wp-content/uploads/2019/09/THR_0919_pg19a-150x150.png)