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Search results for: hyperuricemia

Tigulixostat Promising for Patients with Gout & Hyperuricemia

Arthritis & Rheumatology  |  June 28, 2023

In a dose-finding, clinical trial, Terkeltaub et al. examined the safety and efficacy of tigulixostat, a nonpurine xanthine oxidase inhibitor, for lowering the serum urate levels of patients with gout and hyperuricemia.

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:Arthritis & RheumatologyGoutGout Resource CenterhyperuricemiaResearchserum urate levelstigulixostat

New Study Identifies How Big a Role Diet Plays in Hyperuricemia

Elizabeth Hofheinz, MPH, MEd  |  April 15, 2020

Living like a king has its price. And while kings and queens are primarily something of yesteryear, the vast majority of those living in reasonably wealthy nations can now live like kings. Now, back to that price. Gout, once known as the disease of kings, has been around at least since the time of the…

Filed under:ConditionsGout and Crystalline ArthritisResearch Rheum Tagged with:AlcoholDietGouthyperuricemia

Contemporary Prevalence of Gout & Hyperuricemia in the U.S.

Arthritis & Rheumatology  |  May 31, 2019

Using 2007–2016 data from NHANES, a nationally representative survey of American men and women, Chen-Xu et al. set out to estimate the current prevalence rates and decadal trends of gout and hyperuricemia in the U.S.

Filed under:ConditionsGout and Crystalline ArthritisResearch Rheum Tagged with:Arthritis & RheumatologyGouthyperuricemiaResearchurate-lowering therapies

Research Is Advancing Our Understanding of Gout & Hyperuricemia

Lara C. Pullen, PhD  |  March 19, 2019

CHICAGO—The Gout and Hyperuricemia scientific session at the 2018 ACR/ARHP Annual Meeting opened with a talk by Tony R. Merriman, PhD, a research professor at the University of Otago, New Zealand. His talk focused on molecular epidemiology, with an emphasis on the interactions between genes and environmental exposures, and their contributions to gout. Dr. Merriman…

Filed under:ConditionsGout and Crystalline ArthritisMeeting Reports Tagged with:2018 ACR/ARHP Annual MeetingGoutHuman Functional Genomics Projectshyperuricemia

Hyperuricemia Doesn’t Always Indicate Gout in Rheumatic Disease

Veronika Sharp, MD, Alice Chuang, MD, Lily Kao, MD, RMSK, & Midori Jane Nishio, MD, RhMSUS  |  November 9, 2017

A 57-year-old Ghanaian woman was referred to our rheumatology practice with acute, left elbow swelling and pain. The referring oncologist suspected gout, because the patient had hyperuricemia. Six months before, the patient was diagnosed with stage IV human T-lymphotropic virus type 1 (HTLV-1)-associated adult T cell lymphoma (ATLL). Her initial oncologic manifestations included multiple thoracic,…

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:case reportClinicalDiagnosisGouthyperuricemiamalignantoutcomepatient careRheumatic DiseaserheumatologyT cell lymphomaUltrasound

FDA Approves Duzallo for Hyperuricemia in Patients with Uncontrolled Gout

Reuters Staff  |  August 21, 2017

(Reuters)—Ironwood Pharmaceuticals Inc. said on Monday the U.S. Food and Drug Administration (FDA) approved its oral drug to treat a condition associated with gout. The company’s once-daily drug, Duzallo (lesinurad and allopurinol), was approved to treat hyperuricemia in patients with gout, Ironwood said. Duzallo combines the standard-of-care treatment, allopurinol, with Ironwood’s lesinurad to treat inefficient…

Filed under:ConditionsDrug UpdatesGout and Crystalline Arthritis Tagged with:AllopurinolFDAFood and Drug AdministrationGoutIronwood Pharmaceuticals Inc.lesinurad

Treating Asymptomatic Hyperuricemia Could Lower Risk of Developing Chronic Conditions

Martin Garber, DO  |  August 12, 2016

When uric acid becomes elevated in the human body, a variety of problems can develop, most notably gout—a painful, inflammatory arthritis caused by uric acid crystal deposition in joints. Chronically elevated uric acid can also lead to painful kidney stones. The majority of patients found to have hyperuricemia, however, never go on to develop gout…

Filed under:ConditionsGout and Crystalline ArthritisResearch Rheum Tagged with:ArthritisdiabetesGouthypertensionhyperuricemiaResearchrheumatologyriskTreatmentUric acidvascular disease

Apolipoprotein E Polymorphism Associated with Hyperuricemia in Chinese Population

Lara C. Pullen, PhD  |  December 12, 2014

Researchers find link between hyperuricemia and higher serum uric acid levels in patients with APOE ε2ε3 genotype and APOE-ε2 allele

Filed under:ConditionsGout and Crystalline ArthritisResearch Rheum Tagged with:GouthyperuricemiaResearchrheumatologyUric acid

Letter: Should We Monitor Asymptomatic Hyperuricemia?

William Treuhaft, MD  |  March 1, 2013

Why have physicians stopped routine screening for hyperuricemia and is there any value to this screening?

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:Clinicalhyperuricemiascreening

Prevalence of Gout and Hyperuricemia Increase in U.S.

Sue Pondrom  |  January 18, 2012

Causes include sedentary lifestyle, an increased frequency of obesity and hypertension, diuretic use, and alcohol intake

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:AlcoholDietGoutObesity

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