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Search results for: seropositive

Extracellular Vesicles May Play an Important Role in Seropositive RA Disease Severity

Lara C. Pullen, PhD  |  February 21, 2019

In a study, researchers found extracellular vesicles may contribute to the greater disease severity typically seen in patients with seropositive rheumatoid arthritis (RA). Specifically, in these patients, extracellular vesicles can activate mononuclear phagocytes and induce proinflammatory cytokines in vitro…

Filed under:ConditionsRheumatoid Arthritis

Scientists Pinpoint Three HLA Proteins Linked to Seropositive Rheumatoid Arthritis

Carrie Printz  |  February 28, 2012

Researchers have identified five amino acids in three HLA proteins that explain most of the association between major histocompatibility complex (MHC) and seropositive rheumatoid arthritis (RA).

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:ArthritisBiomarkersRA

Can Stem Cell Transplantation Improve Survival Rates in Patients with Systemic Sclerosis?

Arthritis & Rheumatology  |  April 30, 2025

Autologous hematopoietic stem cell transplantation (AHSCT) may improve the survival rate of patients with diffuse cutaneous systemic sclerosis (SSc), according to Georges et al. The single-arm clinical trial demonstrated the effectiveness of AHSCT and maintenance therapy. Researchers also identified potential risk factor of AHSCT in patients with low eGFR before transplantation.

Filed under:ConditionsSystemic Sclerosis Tagged with:autologous hematopoietic stem cell transplantation (AHSCT)diffuse cutaneous systemic sclerosisSScstem cell transplantationsystemic sclerosis (SSc)

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RA: How High Is the Toll?

Samantha C. Shapiro, MD  |  January 9, 2025

Patients with RA not only suffer from functional limitations, but also face increased healthcare costs, primarily due to prescription drug use, says Dr. Yinan Huang.

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:economic burdenMSPhDphysical burdenRA Resource CenterYinan Huang

MCTD: Is It Just Letters?

Ruth Jessen Hickman, MD  |  December 4, 2024

At a Great Debate session, speakers discussed whether mixed connective tissue disease is a distinct disease entity in rheumatology.

Filed under:ACR ConvergenceConditionsGuidanceMeeting ReportsOther Rheumatic Conditions Tagged with:ACR Convergence 2024connective tissue diseasemixed connective tissue disease (MCTD)

Top Research in Rheumatoid Arthritis Presented at ACR Convergence 2024

Jeffrey Curtis, MD, MS, MPH  |  December 3, 2024

Why this research is relevant to clinicians today & researchers in the future WASHINGTON, D.C.—The ACR Convergence 2024 meeting in Washington, D.C., reflected the continued advancement of science and practical research in the field of rheumatoid arthritis. Highlights this year centered on new RA treatments and new uses of existing treatments; the use of artificial…

Filed under:ACR ConvergenceConditionsGuidanceMeeting ReportsRheumatoid Arthritis Tagged with:ACR Convergence 2024ACR Convergence 2024 RA

Top Research in Psoriatic Arthritis Presented at ACR Convergence 2024

David S. Pisetsky, MD, PhD  |  November 26, 2024

Editor’s note: What research on psoriatic arthritis (PsA) presented at ACR Convergence 2024 has the greatest potential for a positive impact on clinical care, treatment options or serve as the basis for future research? That’s the question The Rheumatologist asked David S. Pisetsky, MD, PhD—our founding editor—to consider. Dr. Pisetsky, a professor of medicine and immunology…

Filed under:ACR ConvergenceConditionsMeeting ReportsPsoriatic ArthritisResearch ReviewsResearch Rheum Tagged with:ACR Convergence 2024ACR Convergence 2024 PsAbone mineral density (BMD)calcium pyrophosphate deposition diseasecardiovascular eventFibromyalgiaFracturesOutcomesSex DifferencesSmokingUltrasound

Interventions to Delay RA Onset

Ruth Jessen Hickman, MD  |  October 9, 2024

Two new successful trials in abatacept, APIPPRA and ARIAA, are the first to convincingly demonstrate the potential of a preventive approach to RA treatment.

Filed under:ConditionsResearch ReviewsResearch RheumRheumatoid Arthritis Tagged with:preventionRA Resource Center

Plan Ahead: Clinical Tips for Managing Reproductive Health in Patients with Rheumatic Disease

Jason Liebowitz, MD, FACR  |  September 24, 2024

Dr. May Ching Soh highlighted practical approaches when caring for pregnant patients with rheumatic disease.

Filed under:ConditionsMeeting Reports Tagged with:APLARAPLAR 2024Asia Pacific League of Associations for Rheumatology (APLAR)pregnancypregnancy complicationspregnant women

Can an App Reduce the Need for In-Person Visits?

Arthritis & Rheumatology  |  April 25, 2024

Solomon et al. examined whether a mobile application (app) for patients with rheumatoid arthritis integrated in the electronic health record would be used by patients and rheumatologists.

Filed under:ConditionsGuidanceResearch RheumRheumatoid Arthritis Tagged with:Arthritis & RheumatologyRA Resource CenterResearchRheumatoid Arthritis (RA)

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