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2015 ACR/ARHP Annual Meeting: Novel Approaches for Intra-Articular Arthritis Therapy

Thomas R. Collins  |  Issue: April 2016  |  April 14, 2016

“The identification of ligands against cartilage extracellular matrix fragments or re­ceptors expressed on OA chondrocytes,” he said, “will further improve the efficacy of nanoparticles carrying drugs aimed at reestablishing the chondrocytes’ homeostatic state.”


Thomas R. Collins is a medical writer based in Florida.

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References

  1. Bajpayee AG, Wong CR, Bawendi MG, et al. Avidin as a model for charge driven transport into cartilage and drug delivery for treating early stage post-traumatic osteoarthritis. Biomaterials. 2014 Jan;35(1):538–549.
  2. Bajpayee AG, Scheu M, Grodzinsky AJ, et al. Electrostatic interactions enable rapid penetration, enhanced uptake and retention of intra-articular injected avidin in rat knee joints. J Orthop Res. 2014 Aug;32(8):1044–1051.
  3. Bajpayee AG, Scheu M, Grodzinsky AJ, et al. A rabbit model demonstrates the influence of cartilage thickness on intra-articular drug delivery and retention within cartilage. J Orthop Res. 2015 May;33(5):660–667.
  4. Bajpayee AG, Quadir MA, Hammond PT, et al. Targeted intra-tissue sustained delivery of dexamethasone using avidin nano-carriers for treating cartilage degeneration. Osteoarthritis Cartilage. 2016 Jan;24(1):71–81.
  5. Sacchetti C, Liu-Bryan R, Magrini A, et al. Polyethylene-glycol-modified single-walled carbon nanotubes for intra-articular delivery to chondrocytes. ACS Nano. 2014 Dec 23;8(12):12280–12291.
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Filed under:ConditionsMeeting ReportsOsteoarthritis and Bone DisordersResearch Rheum Tagged with:2015 ACR/ARHP Annual MeetingAmerican College of Rheumatology (ACR)intra-articular arthritisnano-carriernanotubeOsteoarthritisResearchtherapyTreatment

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