Uveitis is an inflammation of the uvea, which comprises the iris, ciliary body and choroid. Uveitis can lead to ocular damage and complete visual loss.
Explore this issueOctober 2018
Noninfectious etiologies for uveitis are the most common in the U.S.1 The estimated incidence of uveitis ranges from 25–52 per 100,000 in adults and five per 100,000 in children. The prevalence of uveitis ranges from 58–121 cases per 100,000 adults and 13–30 cases per 100,000 children.1-4
Pediatric patients present unique challenges for diagnosis and management.5 These challenges—difficult ophthalmic examinations, delayed diagnosis, medication side effects, adherence to treatment, risk of amblyopia and extended burden of disease into adulthood—require a multidisciplinary approach.6
Symptoms of uveitis vary based on the anatomic location of the inflammation. Among pediatric uveitis cohorts, anterior uveitis is most common, with estimates ranging from 30–70% of total cases.5,7,8 Although usually asymptomatic, anterior uveitis can present with eye redness, pain, tearing and photophobia. In contrast, inflammation in the intermediate and posterior aspects of the uvea often presents with floaters and blurred vision.