Case Report: Digital Ulcers & Weight Loss in a Pediatric Patient

Anusha Vuppala, MD, is a first-year rheumatology fellow at Louisiana State University Health Sciences Center in Shreveport.

Sarwat Umer, MD, is an associate professor of medicine–pediatrics at the Center of Excellence for Arthritis and Rheumatology in Shreveport. Dr. Umer completed her fellowship at Louisiana State University Health Sciences Center, Shreveport, and at UT Southwestern, Dallas. She practices in adult and pediatric rheumatology in Shreveport.

Acknowledgment

The authors thank Samina Qureshi Hayat, MD, for her mentoring, advice and continued support of pediatric rheumatology.

Dr. Hayat is chief and director of the Center of Excellence for Arthritis and Rheumatology, Shreveport, La.

References

1. 1. Papadopoulou C, McCann LJ. The vasculopathy of juvenile dermatomyositis. Front Pediatr. 2018 Oct 9;6:284.
2. 2. Hamaguchi Y, Kuwana M, Hoshino K, et al. Clinical correlations with dermatomyositis-specific autoantibodies in adult Japanese patients with dermatomyositis: A multicenter cross-sectional study. Arch Dermatol. 2011 Apr;147(4):391–398.
3. 3. Sato S, Hoshino K, Satoh T, et al. RNA helicase encoded by melanoma differentiation–associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: Association with rapidly progressive interstitial disease. Arthritis Rheum. 2009 Jul;60(7):2193–2200.
4. 4. Fiorentino D, Chung L, Zwerner J, et al. The mucocutaneous and systemic phenotype of dermatomyositis patients with antibodies to MDA5 (CADM-140): A retrospective study. J Am Acad Dermatol. 2011 Jul;65(1):25–34.
5. 5. Tansley SL, Betteridge ZE, Gunawardena H, et al. Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: A prospective cohort study. Arthritis Res Ther. 2014 July2;16(4);R138.