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Researchers Seek to Predict & Prevent Rheumatoid Arthritis
Preventing adverse outcomes in individuals who have rheumatic diseases is a daily goal for rheumatologists. For example, rheumatologists prescribe medications and perform screening to prevent erosions in rheumatoid arthritis (RA), renal failure in systemic lupus erythematosus and flares across all diseases. Many of these actions are classified as secondary or tertiary prevention, because individuals have…
Antibodies Can Spot RA in the General Population
NEW YORK (Reuters Health)—Anti-citrullinated protein antibodies (ACPA), particularly high anti-CCP2 titers, can diagnose rheumatoid arthritis (RA) in the general population with a high degree of accuracy, a Swedish study suggests. ACPA are highly specific for RA, but until now the diagnostic accuracy of ACPA in the general population has not been “thoroughly assessed,” note Dr….
Industrial Fine Particulate Air Pollution Linked to Increased ACPA Positivity
Researchers investigating the effects of air pollutants on a biomarker for rheumatic autoimmune diseases have found a significant correlation between anti-citrullinated protein antibody positivity in the general population and exposure to industrial fine particulate matter…