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Gene Manipulation Has Potential to Alter Genomes, Impact Society

Simon M. Helfgott, MD  |  Issue: January 2016  |  January 19, 2016

Brave New World indeed.


Simon M. Helfgott, MDSimon M. Helfgott, MD, is associate professor of medicine in the Division of Rheumatology, Immunology and Allergy at Harvard Medical School in Boston.

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References

  1. Lander ES. Brave new genome. N Engl J Med. 2015 Jul 2;373(1):5–8.
  2. Marks L. A healthcare revolution in the making: The story of César Milstein and monoclonal antibodies.
  3. How does CRISPR work? Stat News. 2015 Nov 6.
  4. Grens K. There’s CRISPR in your yogurt. The Scientist. 2015 Jan 1.
  5. Kahn J. The Crispr quandary. The New York Times. 2015 Nov 9.
  6. Knight SC, Xie L, Deng W, et al. Dynamics of CRISPR-Cas9 genome interrogation in living cells. Science. 2015 Nov 13;350(6262):823–826. doi: 10.1126/science.aac6572.
  7. Burt A. Site-specific selfish genes as tools for the control and genetic engineering of natural populations. Proc Biol Sci. 2003 May 7;270(1518):921–928. doi: 10.1098/rspb.2002.2319.
  8. Gantz VM, Jasisnskiene N, Tatrenkova O, et al. Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi. PNAS. 2015 Oct;112(49):E6736–E6743.
  9. Ledford H. CRISPR, the disruptor. Nature. 2015 Jun 4;522(7554):20–24. doi: 10.1038/522020a.
  10. Begley S. Gene drive gives scientists power to hijack evolution. Stat News. 2015 Nov 17.
  11. Cyranoski D, Reardon S. Chinese scientists genetically modify human embryos. Nature. 2015 Apr 22.

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Filed under:OpinionRheuminationsSpeak Out Rheum Tagged with:discoverygenegenomeimpactpublic healthscience

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