Novel Mechanisms of Gout Explored

Attendees of an ACR Convergence 2024 session titled Gout, Gout, Get Ready for a Bout: Here Come New Mechanisms to Knock You Out will gain an understanding of the molecular mechanisms that contribute to the pathogenesis of gout and the molecular mechanisms triggered to suppress inflammation.

Naomi Schlesinger, MD, of the University of Utah, and Michael Pillinger, MD, of the New York University Grossman School of Medicine, will moderate the session on Nov. 18. The panelists will describe the novel mechanisms that promote inflammation in gout, identify new proteins or pathways that may be potential therapeutic options, and describe the growing relevance of cytokines in the pathogenesis of gout.

Specifically, Martin Herrmann, MD, PhD, the Friedrich-Alexander Universität Erlangen-Nürnberg, Germany, will talk about the role of neutrophil extracellular trap (NETs) in gout and whether NET-borne elastase prevents inflammatory relapse.

Hang-Korng Ea, MD, PhD, Université Paris Cité, will discuss novel biomarkers for gout.

Finally, Khaled Elsaid, PhD, PharmD, Chapman University, Orange, Calif., will talk about emerging targets and provide a summary on the recent progress on the novel mechanisms that could be used to suppress inflammation in gout.

Watch this space for full coverage of the session following ACR Convergence 2024.