Metabolic Syndrome & RA Treatment Response

Additionally, the model fit for metabolic syndrome was superior compared with BMI alone, suggesting metabolic syndrome is more informative to clinical response than a simple assessment of weight or BMI.

Conclusion

In patients with RA, metabolic syndrome was associated with lower response rates to the initiation of an advanced RA therapy, with similar effects for both TNF inhibitor and non-TNF inhibitor treatments.

For complete details, including source material, refer to the full study.   

Excerpted and adapted from:

Baker JF, Reed G, Mikuls TR, et al. Metabolic syndrome, adipokines and response to advanced therapies in rheumatoid arthritis. Arthritis Rheumatol. 2025 Mar;77(3).

The role of adipokines in the pathogenesis of rheumatic diseases

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Conclusion

Excerpted and adapted from:

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