New Guideline Recommends Frequent Monitoring & Collaboration for JIA-Associated Uveitis Management

References

1. Angeles-Han ST, Ringold SR, Beukelman T, et al. 2019 American College of Rheumatology/Arthritis Foundation guideline for the screening, monitoring, and treatment of juvenile idiopathic arthritis-associated uveitis. Arthritis Care Res(Hoboken). 2019 Apr 25. doi: 10.1002/acr.23871. [Epub ahead of print]
2. Angeles-Han ST, Ringold SR, Beukelman T, et al. 2019 American College of Rheumatology/Arthritis Foundation guideline for the screening, monitoring, and treatment of juvenile idiopathic arthritis-associated uveitis. Arthritis Rheumatol. 2019 Apr 25. doi: 10.1002/art.40885. [Epub ahead of print]
3. Ringold SR, Angeles-Han ST, Beukelman T, et al. 2019 American College of Rheumatology/Arthritis Foundation guideline for the treatment of juvenile idiopathic arthritis: Therapeutic approaches for non-systemic polyarthritis, sacroiliitis, and enthesitis. Arthritis Care Res. 2019 Apr 25. doi: 10.1002/acr.23870. [Epub ahead of print]
4. Ringold SR, Angeles-Han ST, Beukelman T, et al. 2019 American College of Rheumatology/Arthritis Foundation guideline for the treatment of juvenile idiopathic arthritis: Therapeutic approaches for non-systemic polyarthritis, sacroiliitis, and enthesitis. Arthritis Rheumatol. 2019 Apr 25. doi: 10.1002/art.40884. [Epub ahead of print]
5. Parker DM, Angeles-Han ST, Stanton AL, Holland GN. Chronic anterior uveitis in children: Psychosocial challenges for patients and their families. Am J Ophthalmol. 2018 Jul;191:xvi–xxiv. doi: 10.1016/j.ajo.2018.03.028.

Table notes: Each recommendation had very low-quality level of evidence.

High-risk children are those with oligoarthritis, polyarthritis (rheumatoid factor negative), psoriatic arthritis, or undifferentiated arthritis who are also anti-nuclear antibody positive, younger than 7 years of age at JIA onset, and have JIA duration of four years or less.

Definition of new CAU activity: no prior uveitis or loss of control of previously controlled uveitis.

Strong recommendations are those for which the guideline voting panel was confident the benefits of the action outweigh the risks and would apply to most or all patients. Conditional recommendations are those for which the voting panel had less confidence in the risk-benefit assessment, with a preference for shared decision making.

Table key: JIA = juvenile idiopathic arthritis; PICO = patient/population, intervention, comparison and outcomes; CAU = chronic anterior uveitis; DMARDs = disease- modifying anti-rheumatic drugs; TNFi = tumor necrosis factor inhibitor; AAU = acute anterior uveitis.