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New Insights into the Structure of Collagen Fibril

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“Our data suggest that fiber breakdown during osteoarthritis initially occurs by ‘unbundling’ of prototypic fibrils, suggesting a potential target for therapy,” write the authors.

Lara C. Pullen, PhD, is a medical writer based in the Chicago area.

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Reference

  1. Gottardi R, Hansen U, Raiteri R, et al. Supramolecular organization of collagen fibrils in healthy and osteoarthritic human knee and hip joint cartilage. PLoS One. 2016 Oct 25;11(10):e0163552. doi: 10.1371/journal.pone.0163552. eCollection 2016.

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