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From the Expert: New Advances in Treatment of Systemic Scleroderma

Richard Quinn  |  April 22, 2016

A recent study found that mycophenolate mofetil is an effective alternative for the treatment of systemic scleroderma with interstitial lung disease, resulting in possible long-term improvement. According to Aryeh Fischer, MD, this new research points to the future expansion of treatment options…

OA Knee Pain Treatment Enters Clinical Trials, Ixekizumab Receives FDA Approval & Belimumab Promising for SLE Patients

Michele B. Kaufman, PharmD, BCGP  |  April 20, 2016

Clinical trials have begun to determine if disodium zoledronate tetrahydrate is safe and effective for treating pain in patients with knee osteoarthritis. The FDA has approved the use of ixekizumab for the treatment of plaque psoriasis. And a study has shown that patients with SLE treated with belimumab may be able to decrease steroid use…

CMS Commences 45-Day Open Payments Review & Dispute Period

From the College  |  April 18, 2016

On April 1, the Centers for Medicare and Medicaid Services (CMS) announced the beginning of the 45-day Open Payments Review and dispute period, which will conclude on May 15. After the review period concludes, on June 30, CMS will publish 2015 payment data along with updates to the 2013 and 2014 data. If you are…

Platelet-Rich Plasma Therapy May Treat Degenerative Tendinopathies & Pain

Lara C. Pullen, PhD  |  April 18, 2016

A recent small-scale study showed that patients who received platelet-rich plasma therapy for tendon healing experienced clinically important improvements in pain and disability compared with placebo. Additionally, MRI showed that some participants had improvement in the pathoanatomy of the rotator cuff six months after treatment…

Sifalimumab Shows Some Promise Against Lupus

Reuters Staff  |  April 15, 2016

NEW YORK (Reuters Health)—Sifalimumab, an anti-interferon alpha monoclonal antibody, may lead to some improvement in patients with systemic lupus erythematosus (SLE), according to a new trial. In a paper online on March 23 in Annals of the Rheumatic Diseases, Dr. Munther Khamashta of King’s College London and colleagues note that treatment of SLE presents a…

A Long Way to Go: Treating Pain in Patients with Inflammation

Richard Quinn  |  April 15, 2016

Subjectivity and the differences in how patients with autoimmune and other diseases perceive pain make the study and treatment of pain difficult. But Yvonne Lee, MD, says future advances in neuroimaging may aid in the objective study of pain and innovative treatments…

Hidradenitis Suppurativa Can Complicate Biologic Therapy

Will Boggs, MD  |  April 13, 2016

NEW YORK (Reuters Health)—Hidradenitis suppurativa can complicate biologic therapy of chronic inflammatory diseases, according to a retrospective study from France and Belgium. Hidradenitis suppurativa (HS) often responds to treatment with biologic agents, but there have been scattered reports of patients developing HS while undergoing biologic therapy. Dr. Coline Faivre from Hôpital Edouard Herriot in Lyon,…

Etanercept Submitted to FDA for Approval to Treat Pediatric Plaque Psoriasis; Boehringer Ingelheim & AbbVie to Collaborate; Low Doses of Gerilimzumab Promising for RA

Michele B. Kaufman, PharmD, BCGP  |  April 13, 2016

The FDA has received an application to expand the use of etanercept to treat plaque psoriasis in pediatric patients. Boehringer Ingelheim and AbbVie have announced a collaborative partnership to develop treatments for multiple autoimmune diseases. And gerilimzumab may prove safe and effective for treating inflammatory diseases at very low doses…

Carpal Tunnel Syndrome: Is Post-Surgical Rehabilitation Helpful?

Lara C. Pullen, PhD  |  April 11, 2016

A recent research review compared the results of various studies on rehabilitation treatments, including immobilization, exercise and cold therapy, for patients with carpal tunnel syndrome after surgery. The authors concluded that little evidence supports the effectiveness of rehabilitation techniques, and many of the studies reviewed have similar limitations…

From the Expert: Don’t Forget to Vaccinate Immuncompromised Patients

Richard Quinn  |  April 8, 2016

Preventing infection in immunocompromised patients is challenging, especially with the increased use of biologic treatments, which have been known to reactivate latent infections, such as the herpes zoster virus. Nicolas Issa, MD, discusses recent vaccination research and prevention techniques to help this patient group avoid infection…

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