ZURICH (Reuters)—The U.S. Food and Drug Administration (FDA) has rejected Novartis’s bid to repurpose a drug now approved for rare inflammatory diseases to be used in a group of heart attack survivors, according to the Swiss drugmaker. The company received an FDA letter turning down its bid to make canakinumab a targeted therapy for those…

Plaque Psoriasis Treatments: BMS-986165 Promising & Adalimumab Biosimilar Demonstrates Equivalence
According to new data, BMS-986165, an oral, selective tyrosine kinase 2 inhibitor, may be safe and effective for treating plaque psoriasis…

Uveitis: Know the Risk Factors, Symptoms & Treatment Options
Inflammatory diseases can cause uveitis. Early detection and treatment are essential, but when uveitis goes undetected it can cause blindness. Here’s how to protect your patients…

ARHP Lifetime Achievement Award Winner: Christina H. Opava, PhD, RPT
CHICAGO—Christina H. Opava, PhD, RPT, is the recipient of the 2018 ARHP Lifetime Achievement Award, which was presented (along with the other ACR and ARHP awards) during the opening session of the 2018 ACR/ARHP Annual Meeting on Oct. 20. “Receiving this award is an immense honor,” she tells The Rheumatologist. “My first thought was that…

Are Bending & Lifting Associated with Lumbosacral Radiculopathy Syndrome?
Patients with lumbosacral radiculopathy syndrome (LRS) may wonder if physicality of their jobs contributed to the development of their symptoms. A recent systematic review sought to identify LRS work-related risk factors. Researchers found that bending and lifting of the trunk, both alone and in combination, may contribute to LRS…

Heart of a Champion: The 2018 ACR/ARHP Annual Meeting Kicks Off with Dramatic Keynote
“You’re probably going to die tonight. You should call your family.” Jonathan Koch, president and CCO of Asylum Entertainment LLC, told his touching and inspiring story of mysterious illness, resilience and recovery in the keynote presentation of the 2018 ACR/ARHP Annual Meeting.

Ethics Forum: When & How to Intervene with the Impaired Colleague
You are seeing a hospital consult late in the afternoon on a Saturday. The patient has suspected, new-onset lupus with inflammatory arthritis, renal failure with nephrotic range proteinuria and a malar rash. You plan to start the patient on high-dose IV steroids, and you decide to speak to the nephrologist on call first. When he…

Dr. Chris Phillips Competes in Triathlons
“I think I’m mentally sharper when I have been exercising and taking care of myself,” says Chris Phillips, MD, a rheumatologist in solo practice in Paducah, Ky. Dr. Phillips has recognized these benefits since high school, when he began participating in competitive sports. Four years ago, Dr. Phillips was competing against 40 other cyclists in…

Awards, Appointments & Announcements in the World of Rheumatology
Canadian Pediatric Rheumatologist Invested into Order of Canada Peter Dent, MD, professor emeritus of pediatrics at McMaster University in Hamilton, Ontario, Canada, was invested into the Order of Canada in May. The Order of Canada is the country’s highest civilian honor. “Dr. Dent has had a substantial positive impact on healthcare, in Hamilton and far…

Trimethoprim-Sulfamethoxazole Prophylaxis Reduced Rituximab Infection Risk
Severe infections occurred in 25% of patients with anti-neutrophil cytoplasm antibody (ANCA) associated vasculitis (AAV) who were treated with rituximab, according to results of an observational study conducted in the United Kingdom (U.K.) and Austria. Trimethoprim-sulfamethoxazole (TMP/SMX) prophylaxis, however, reduced the risk of severe infections, the investigators reported in Annals of the Rheumatic Diseases.1 Andreas…
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