WASHINGTON (Reuters)—The U.S. Supreme Court on Monday declined to hear a case over whether companies that make copycat versions of biologic drugs must wait six months after winning federal approval before bringing them to the market. The justices opted not to take up Apotex Inc.’s appeal of a July federal appeals court ruling that could…
Trump Considering Dr. Scott Gottlieb to Head U.S. FDA
(Reuters)—Dr. Scott Gottlieb, a partner at one of the world’s largest venture capital funds and a former deputy commissioner at the U.S. Food and Drug Administration, is being considered by President-Elect Donald Trump to run the agency, according to sources close to the transition team. Gottlieb, 44, a venture partner at New Enterprise Associates and…
Location & Ethnicity Affect Manifestations of Primary Sjogren’s Syndrome
NEW YORK (Reuters Health)—Geolocation and ethnicity exert a “strong influence” on the phenotype of primary Sjogren’s syndrome, researchers report. “The influence of ethnicity on the phenotypic expression of systemic autoimmune diseases has been suggested by various studies, especially in systemic lupus erythematosus, which has been reported as being more frequent and having less favorable outcomes…

Fecal Metabolomics Implicate Tryptophan Pathway in Pediatric Spondyloarthritis
Using metabolomic profiling of fecal samples of children with enthesitis-related arthritis (ERA), researchers found that children with ERA may have lower levels of tryptophan metabolites. This finding may be attributable to differences in the gut microbiota that contribute to their pro-inflammatory phenotype…

Obesity & Rheumatic Disease
“Obesity is an inflammatory state, so it is in the landscape of the rheumatologist,” says Christopher Ritchlin, MD, MPH. And the more attention rheumatologists pay to obesity, the better…
Japan PM’s Advisers Urge Annual Review of Drug Prices
TOKYO (Reuters)—Prime Minister Shinzo Abe’s economic advisers, hoping to curb Japan’s ballooning healthcare costs, proposed on Wednesday reforms to the way drug prices are set, a step opposed by foreign and domestic drug makers who say the changes will stifle investment. The proposals follow a decision to halve the price of Bristol Myers Squibb Co’s…
Malignancy Risk in ANCA-Associated Vasculitis Is Lower with Rituximab
NEW YORK (Reuters Health)—Compared with cyclophosphamide, rituximab treatment poses less malignancy risk in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), European researchers report. Dr. Emma E. van Daalen of Leiden University Medical Center in the Netherlands tells Reuters Health, “Previous studies reported an increased malignancy risk in patients with AAV, which has been associated…
U.S. Insurer Lobby Group Seeks Delay in 2018 Obamacare Deadline
NEW YORK (Reuters)—The largest lobbying group for health insurers has asked U.S. lawmakers weighing the fate of Obamacare to push back the due date for 2018 individual insurance submissions to regulators in hopes of obtaining greater clarity on the program’s future later on. Republican leaders including President-elect Donald Trump and U.S. Senate Majority Leader Mitch…
New GAC Chair Picks up the Baton
It’s an honor and a thrill to be the next chair of the Government Affairs Committee. Boy, do we have a big year ahead.

Celecoxib & Cardiovascular Death: NSAID Safety Under Review
A recent study showed that at moderate doses celecoxib may be noninferior with respect to cardiovascular safety compared with ibuprofen or naproxen…
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