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Rectosigmoidoscopy vs. Colonoscopy for Assessing Ulcerative Colitis Activity

Reuters Health  |  October 30, 2015

NEW YORK (Reuters Health)—In most cases, rectosigmoidoscopy and colonoscopy assessments of disease activity in ulcerative colitis yield the same results, researchers report. “In clinical practice, rectosigmoidoscopy is enough to assess endoscopic activity and endoscopic healing,” Dr. Jean-Frédéric Colombel from Icahn School of Medicine at Mount Sinai, N.Y., told Reuters Health by email. Dr. Colombel and…

Signatures to Be Filed for California Drug Price Referendum

Sharon Bernstein  |  October 30, 2015

SACRAMENTO, Calif. (Reuters)—Backers of a referendum aimed at reducing the cost of prescription drugs in California said Wednesday that they had gathered more than enough signatures to place their measure on the November 2016 ballot in the most populous U.S. state. The measure by the AIDS Healthcare Foundation would require the state to pay no…

Sleep Apnea Tied to Gout Flares

Kathryn Doyle  |  October 30, 2015

NEW YORK (Reuters Health)—Sleep apnea may increase the risk of developing gout and experiencing flare-ups, according to a new study. Until now, little was known about the relationship between the two conditions, the study team writes in an article online Oct. 19 in Arthritis & Rheumatology. Obesity plays an important role in both sleep apnea…

Specialized Health Care May Be Lacking under Obamacare Plans

Andrew M. Seaman  |  October 29, 2015

(Reuters Health)—Some health insurance plans sold on the Affordable Care Act‘s federal marketplace may not provide reasonable access to medical specialists, new research suggests. Under the act, also known as Obamacare, the federal marketplace offers subsidized private health insurance to consumers in states that didn’t establish their own health insurance exchanges. About one in seven…

Don’t Bank on U.S. Drug Price Rises, Warns GSK Boss

Ben Hirschler  |  October 29, 2015

LONDON (Reuters)—Pharmaceutical companies cannot depend on ever increasing prices in the U.S. and will need to find a new balance between incentives for innovation and access to medicines, according to the chief executive of GlaxoSmithKline. High drug prices have come under fierce political fire recently in America, the industry’s biggest and most profitable market, with…

Low-Grade Inflammation in Symptomatic Knee OA

Arthritis & Rheumatology  |  October 29, 2015

Although osteoarthritis (OA) was formerly considered a non-inflammatory joint disease, it’s now well-appreciated that inflammatory mediators, such as PGE2 and IL-1β, are produced by osteoarthritic joint tissues and can be used to identify patients with symptomatic knee OA. A peripheral blood leukocyte inflammatory transcriptome identifies a subset of symptomatic knee OA patients at higher risk for radiographic progression and may reflect persistent low-grade joint inflammation…

The Lupus Initiative Receives 5-Year CDC Grant

American College of Rheumatology  |  October 28, 2015

The Centers for Disease Control and Prevention (CDC) has awarded the American College of Rheumatology’s (ACR) The Lupus Initiative (TLI) with a five-year grant to support the development of a national, grassroots program targeting primary care providers, persons with undiagnosed Lupus and rheumatology health care providers. The program will have three components: Immediate dissemination of…

Tofacitinib on Hold for Psoriasis, Plus Anti-TNFs Top FDA List for Adverse Events

Michele B. Kaufman, PharmD, BCGP  |  October 28, 2015

The FDA is asking for more safety analysis before approving tofacitinib to treat psoriasis. Also, adalimumab and etanercept received the greatest number of adverse and serious adverse events reported to the FDA in 2014…

Genetic Screening May Prevent Adverse Gout Treatment Reaction

Lara C. Pullen, PhD  |  October 26, 2015

Screening gout patients for the HLA-B*58:01 allele may help rheumatologists determine more effective treatments and a patient’s risk of allopurinol-induced severe cutaneous adverse reactions…

BMI Feasible As Pre-Screening Tool for Osteoporosis in Women

Larry Hand  |  October 24, 2015

NEW YORK (Reuters Health)—A body mass index (BMI) of less than 28 alone may be a tool to prescreen younger postmenopausal women for osteoporosis, according to a new study. “For young postmenopausal white women aged 50–64, current prescreening modalities identifying candidates for DXA (dual-energy X-ray absorptiometry) scan … are not performing better than BMI alone,”…

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