Approximately half of the patients (22) with periodontitis and RA received periodontal treatment, oral hygiene instruction and full-mouth supragingival scaling with ultrasonic instruments. Blood work was again performed two months after periodontal treatment on these patients, revealing that serum levels of CarP and NETs significantly decreased post-treatment, even though the distribution and dose of RA treatment with corticosteroids, NSAIDs or conventional synthetic disease-modifying anti-rheumatic drugs were the same at baseline and reassessment. The authors concluded their paper by suggesting that there may be an underlying shared pathogenic mechanism behind RA and periodontitis.
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Lara C. Pullen, PhD, is a medical writer based in the Chicago area.
- Kaneko C, Kobayashi T, Ito S3, et al. Circulating levels of carbamylated protein and neutrophil extracellular traps are associated with periodontitis severity in patients with rheumatoid arthritis: A pilot case-control study. PLoS One. 2018 Feb 2;13(2):e0192365. doi: 10.1371/journal.pone.0192365. eCollection 2018.