The frequency of adverse events and serious adverse events, including those that led to therapy discontinuation, was low and similar across all study groups. No new safety signals were identified.
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This study showed that adding ixekizumab to conventional background medications was superior to conventional background medication alone for improving the signs, symptoms and inflammation on MRI in patients with non-radiographic axSpA.
Michele B. Kaufman, PharmD, BCGP, is a freelance medical writer based in New York City and a pharmacist at New York Presbyterian Lower Manhattan Hospital.
- Deodhar A, van der Heijde D, Gensler L, et al. Ixekizumab in non-radiographic axial spondyloarthritis: Primary results from a phase 3 trial [abstract #2729]. Arthritis Rheumatol. 2019 Oct; 71(suppl 10).