MRI is a potentially powerful tool to identify proteoglycan and collagen loss, both possibly meaningful changes seen early after joint injury.
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“We have to prevent collagen loss, because that occurs early on. There is a narrow window, but I think we can prevent a lot of the OA afterward,” he concluded. Proteomic analysis may tell us about gene markers that predict who is likely to develop post-traumatic OA after surgery and reveal more clues on why some people resolve their inflammation while others do not.
Susan Bernstein is a freelance medical journalist based in Atlanta.
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