DISRs may resolve after discontinuation of the offending agent and recur if the agent is reintroduced. Among the medications that more commonly cause DISR are immune checkpoint inhibitors, highly active anti-retroviral therapies, tumor necrosis factor- α antagonists and BRAF inhibitors. It’s important to keep drug reactions in mind when evaluating patients with sarcoid-like symptoms and signs.
In Sum
A great deal remains to be discovered about sarcoidosis. For rheumatologists and other clinicians, this disease will continue to be part of the deferential for many patients, and hopefully, the coming years will allow for its effective diagnosis and treatment.
Jason Liebowitz, MD, completed his fellowship in rheumatology at Johns Hopkins University, Baltimore, where he also earned his medical degree. He is currently in practice with Skylands Medical Group, N.J.
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