The Rheumatologist
COVID-19 News
  • Connect with us:
  • Facebook
  • Twitter
  • LinkedIn
  • YouTube
  • Feed
  • Home
  • Conditions
    • Rheumatoid Arthritis
    • SLE (Lupus)
    • Crystal Arthritis
      • Gout Resource Center
    • Spondyloarthritis
    • Osteoarthritis
    • Soft Tissue Pain
    • Scleroderma
    • Vasculitis
    • Systemic Inflammatory Syndromes
    • Guidelines
  • Resource Centers
    • Ankylosing Spondylitis Resource Center
    • Gout Resource Center
    • Rheumatoid Arthritis Resource Center
    • Systemic Lupus Erythematosus Resource Center
  • Drug Updates
    • Biologics & Biosimilars
    • DMARDs & Immunosuppressives
    • Topical Drugs
    • Analgesics
    • Safety
    • Pharma Co. News
  • Professional Topics
    • Ethics
    • Legal
    • Legislation & Advocacy
    • Career Development
      • Certification
      • Education & Training
    • Awards
    • Profiles
    • President’s Perspective
    • Rheuminations
  • Practice Management
    • Billing/Coding
    • Quality Assurance/Improvement
    • Workforce
    • Facility
    • Patient Perspective
    • Electronic Health Records
    • Apps
    • Information Technology
    • From the College
    • Multimedia
      • Audio
      • Video
  • Resources
    • Issue Archives
    • ACR Convergence
      • Systemic Lupus Erythematosus Resource Center
      • Rheumatoid Arthritis Resource Center
      • Gout Resource Center
      • Abstracts
      • Meeting Reports
      • ACR Convergence Home
    • American College of Rheumatology
    • ACR ExamRheum
    • Research Reviews
    • ACR Journals
      • Arthritis & Rheumatology
      • Arthritis Care & Research
      • ACR Open Rheumatology
    • Rheumatology Image Library
    • Treatment Guidelines
    • Rheumatology Research Foundation
    • Events
  • About Us
    • Mission/Vision
    • Meet the Authors
    • Meet the Editors
    • Contribute to The Rheumatologist
    • Subscription
    • Contact
  • Advertise
  • Search
You are here: Home / Articles / Survivin Essential for the Maturation of Antigen Presenting Cells in Rheumatoid Arthritis Patients

Survivin Essential for the Maturation of Antigen Presenting Cells in Rheumatoid Arthritis Patients

January 2, 2013 • By Lara C. Pullen, PhD

  • Tweet
  • Email
Print-Friendly Version / Save PDF

When asked about the clinical implications of her study, Dr. Bokarewa responded by e-mail that, “For general practitioners and for rheumatologists, I would recommend to test the levels of survivin in blood circulation. High levels will indicate patients with severe and joint-destructive disease. High levels of survivin are tightly connected with progression of joint destruction and poor response to antirheumatic treatment. It is a valuable parameter to analyze in parallel with such accredited parameters as rheumatoid factor and antibodies to cyclic citrulinated peptides.”

You Might Also Like
  • New Research Focuses on Bone Erosion and Repair in Rheumatoid Arthritis
  • TNF-α Impairs Regulatory T Cells in Patients with Rheumatoid Arthritis
  • Clues Emerge to Bone Health, Destruction in Rheumatoid Arthritis
Also By This Author
  • Pathophysiology of Gouty Tophi

She added, “We have preliminary data which would show that survivin (or survivin-related proteins) is a promising therapeutic target in arthritis.”

ad goes here:advert-1
ADVERTISEMENT
SCROLL TO CONTINUE

 

Dr. Pullen is a medical writer based in the Chicago area.

ad goes here:advert-2
ADVERTISEMENT
SCROLL TO CONTINUE

Reference

1. Andersson SE, Svensson MN, Erlandsson MC, Dehlin M, Andersson KM, Bokarewa MI. Activation of Fms-like tyrosine kinase 3 signaling enhances survivin expression in a mouse model of rheumatoid arthritis. PLoS One. 2012;7:e47668.

 

ad goes here:advert-3
ADVERTISEMENT
SCROLL TO CONTINUE

Pages: 1 2 | Single Page

Filed Under: Conditions, Research Reviews, Rheumatoid Arthritis Tagged With: RA, Rheumatoid arthritis, survivin

You Might Also Like:
  • New Research Focuses on Bone Erosion and Repair in Rheumatoid Arthritis
  • TNF-α Impairs Regulatory T Cells in Patients with Rheumatoid Arthritis
  • Clues Emerge to Bone Health, Destruction in Rheumatoid Arthritis
  • Plasma Cells, Synovial Compartment Implicated in Tenacity of Rheumatoid Arthritis

Meeting Abstracts

Browse and search abstracts from the ACR Convergence and ACR/ARP Annual Meetings going back to 2012.

Visit the Abstracts site »

American College of Rheumatology

Visit the official website for the American College of Rheumatology.

Visit the ACR »

Simple Tasks

Learn more about the ACR’s public awareness campaign and how you can get involved. Help increase visibility of rheumatic diseases and decrease the number of people left untreated.

Visit the Simple Tasks site »

The Rheumatologist newsmagazine reports on issues and trends in the management and treatment of rheumatic diseases. The Rheumatologist reaches 11,500 rheumatologists, internists, orthopedic surgeons, nurse practitioners, physician assistants, nurses, and other healthcare professionals who practice, research, or teach in the field of rheumatology.

About Us / Contact Us / Advertise / Privacy Policy / Terms of Use

  • Connect with us:
  • Facebook
  • Twitter
  • LinkedIn
  • YouTube
  • Feed

Copyright © 2006–2021 American College of Rheumatology. All rights reserved.

ISSN 1931-3268 (print)
ISSN 1931-3209 (online)

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.