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You are here: Home / Articles / Synthetic DMARDs May Blunt Pneumococcal Vaccine Response in Systemic Sclerosis

Synthetic DMARDs May Blunt Pneumococcal Vaccine Response in Systemic Sclerosis

January 24, 2018 • By Scott Baltic

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However, Dr. John Varga, of the Northwestern University Feinberg School of Medicine, Chicago, tells Reuters Health in a phone interview, “I would be extremely cautious” about extrapolating these findings to other rheumatic diseases, noting SSc has features, such as fibrosis, that set it aside from other rheumatic diseases.

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The study was well done, with clean results, Dr. Varga adds, but it was based on a small cohort (from southern Sweden) that’s unlikely to have had much ethnic diversity.

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Reference

  1. Hesselstrand R, Nagel J, Saxne T, et al. Immunogenicity and safety of pneumococcal vaccination in patients with systemic sclerosis. Rheumatology (Oxford). 2018 Jan 8. doi: 10.1093/rheumatology/kex471. [Epub ahead of print]

 

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Filed Under: Conditions Tagged With: disease-modifying antirheumatic drugs, DMARDs, pneumococcal vaccine, sclerosis, Systemic sclerosis

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