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Zoledronic Acid vs. Oral Bisphosphonates: Osteoporosis Treatments & the Risk of Developing Osteonecrosis of the Jaw

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Michele B. Kaufman, PharmD, BCGP, is a freelance medical writer based in New York City and a pharmacist at New York Presbyterian Lower Manhattan Hospital.

References

  1. Highlights of prescribing information: Zometa (zoledronic acid). U.S. Food & Drug Administration. 2019 Dec 12.
  2. Rosen HN. Bisphosphonate therapy for the treatment of osteoporosis. Up-To-Date. 2022 Jul 21.
  3. Moore N, Noblet C, Kreft-Jais C, et al. La banque de cas du système français de pharmacovigilance: quelques exemples d’exploitation [French pharmacovigilance database system: examples of utilisation]. Therapie. 1995 Nov–Dec;50(6):557–562. French. PMID: 8745956.
  4. Amigues C, Fresse A, Roux C, et al. Zoledronate-related osteonecrosis of the jaw in osteoporosis: Incidence, risk factors and comparison to oral bisphosphonates [OP0240]. Ann Rheum Dis. 2022;81 (suppl 1):158.

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