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An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

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Conditions

Subcategories:Axial SpondyloarthritisGout and Crystalline ArthritisGuidelinesMyositisOsteoarthritis and Bone DisordersOther Rheumatic ConditionsPain SyndromesPediatric ConditionsPsoriatic ArthritisRheumatoid ArthritisSjögren’s DiseaseSoft Tissue PainSystemic Lupus ErythematosusSystemic SclerosisVasculitis

A Historical Look at the Characterization of Lupus as a Systemic Disease

Ruth Jessen Hickman, MD  |  October 18, 2018

The disease called systemic lupus erythematosus (SLE) went through many different stages of classification before reaching the modern criteria reflecting our current understanding of its pathogenesis. In 1872, the Viennese dermatologist Moriz Kaposi, MD, published a paper, “New Contributions to Knowledge of Lupus Erythematosus,” which provided a significant leap forward in the characterization of this…

An Overview of Pediatric, Noninfectious Uveitis

Joseph McDonald, MD, Virginia Miraldi Utz, MD, & Sheila T. Angeles-Han, MD, MS  |  October 18, 2018

Uveitis is an inflammation of the uvea, which comprises the iris, ciliary body and choroid. Uveitis can lead to ocular damage and complete visual loss. Noninfectious etiologies for uveitis are the most common in the U.S.1 The estimated incidence of uveitis ranges from 25–52 per 100,000 in adults and five per 100,000 in children. The…

The Case of a 13-Year-Old Girl with Life-Threatening Lupus Onset

Charles Radis, DO  |  October 18, 2018

I glanced up from Amanda Wolf’s chart as the emergency department nurse, followed by the lab technician (tech), followed by the electrocardiogram (ECG) tech flowed into cubicle No. 5. John Benner, MD, pulled up a chair to review the case with me at the nursing station. “Here’s what we’ve got. Thirteen-year-old girl with a one-week…

Genes, Not Diet, Main Determinant of Urate Levels

Anne Harding  |  October 17, 2018

NEW YORK (Reuters Health)—Heredity plays a substantially larger role than diet in determining serum urate levels, according to new findings in BMJ. Nearly 25% of the variation in serum urate is attributable to common genetic variants, while dietary pattern explained less than 1%, Dr. Tanya J. Major of the University of Otago in Dunedin, New…

Older Gout Patients More Likely to Develop Hearing Impairment

Lara C. Pullen, PhD  |  October 15, 2018

Previous research has established that gout and hearing loss have shared risk factors. Now, a recent study found gout itself is associated with an increased risk of hearing loss in adults 65 years and older…

Social Media May Reduce Depression Risk for Older People with Pain

Cheryl Platzman Weinstock  |  October 10, 2018

(Reuters Health)—Online socializing may weaken the tie between pain and depression for older people, a U.S. study suggests. People in chronic pain are at risk of depression to start with. When pain makes them stay home more, interacting with friends and family less, it only adds to this risk, the researchers write in the Journals…

Revised Application Expected for IV Meloxicam; Plus EU Approves Tildrakizumab

Michele B. Kaufman, PharmD, BCGP  |  October 9, 2018

After meeting with the FDA, the makers of intravenous meloxicam plan to resubmit the treatment’s new drug application…

Allopurinol for Gout an Unlikely Contributor to Kidney Disease

Reuters Staff  |  October 8, 2018

NEW YORK (Reuters Health)—Allopurinol does not appear to contribute to decline in kidney function and may actually protect renal function in patients with gout, according to a large population-based study. Gout affects around 4% of Americans and often occurs alongside chronic kidney disease (CKD), Dr. Tuhina Neogi from Boston University School of Medicine and colleagues…

Taking Vitamin D Supplements May Not Improve Bone Health

Linda Carroll  |  October 7, 2018

(Reuters Health)—Vitamin D supplementation may not improve bone density or prevent fractures and falls in adults, a large new analysis suggests. After combining data from 81 randomized controlled trials, researchers found no bone benefits from supplementing the vitamin, according to the report in The Lancet Diabetes & Endocrinology, online October 4. “Our results show that…

Trio Wins Chemistry Nobel for Work on Antibody Drugs & Detergents

Daniel Dickson and Ben Hirschler  |  October 4, 2018

STOCKHOLM/LONDON (Reuters)—Two Americans and a Briton won the 2018 Nobel Prize for Chemistry on Wednesday for harnessing the power of evolution to generate novel proteins used in everything from environmentally friendly detergents and biofuels to cancer drugs. The fruits of this work include the world’s top-selling prescription medicine – the antibody injection Humira sold by…

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