Researchers have determined that dominant B cell receptor (BCR) clones in peripheral blood may predict the onset of clinical signs and symptoms of RA…
Osteoporosis Drugs Tied to Lower Fracture Risk & Health Costs
(Reuters Health)—Older women with osteoporosis who consistently take a bisphosphonate may have a lower risk of fractures and lower total health costs than their counterparts who stop taking these drugs, a U.S. study suggests. Researchers examined data on 294,369 women who were at least 66 years old, insured by Medicare and prescribed osteoporosis medicines for…
Adalimumab Appears Safe for Treating Pediatric Patients with Autoimmune Disease
NEW YORK (Reuters Health)—Adalimumab appears to be safe for treating pediatric patients with polyarticular juvenile idiopathic arthritis (JIA), enthesitis-related arthritis (ERA), psoriasis and Crohn’s disease (CD), according to data from company-sponsored clinical trials. Adalimumab is an anti-tumor necrosis factor monoclonal antibody with demonstrated efficacy in these conditions, but pediatric safety data remains limited. Dr. Gerd…
Chikungunya Fever May Trigger Chronic Articular Symptoms
NEW YORK (Reuters Health)—More than half of those infected by the mosquito-borne Chikungunya virus will go on to experience chronic articular pain or arthritis, according to Brazilian researchers. Chikungunya—meaning “to become contorted” in the Makonde language—was first described during an outbreak in Africa in the 1950s. Many outbreaks have since occurred in Africa, Asia and…
Gene Expression Signature Useful for Diagnosing Kawasaki Disease
NEW YORK (Reuters Health)—A 13-transcript whole-blood gene expression signature accurately differentiates Kawasaki disease (KD) from other febrile conditions in children, researchers report. “We believe it is feasible to turn the signature into a diagnostic test,” Dr. Michael Levin from Imperial College London, London, tells Reuters Health by email. “There are a range of methods to…
5 Takeaways from the ACR’s Gout Clinical Quality Measures
With electronic clinical quality measures tailored for treating gout patients, physicians and their teams now have tools to measure and improve gout care performance and outcomes…
Effects of Obesity on Sustained Remission in Early RA
A new study examined the independent effects of excess weight and obesity on achieving sustained remission in rheumatoid arthritis (RA) patients. Researchers found that within three years of RA diagnosis, overweight and obese patients were significantly less likely to achieve sustained remission than patients with healthy body mass indices (BMIs). Higher BMIs were also associated with persistent disease activity…
ACR Seeks CMS Exemption to Perform Synovial Fluid Crystal Analysis
Marcus Snow, MD, is a rheumatologist in a multispecialty clinic in Nebraska. During the average day, the nephrologist in his clinic can assess urinary sediment. The urologist can examine semen specimens for viability. However, despite clinical training and competency, Dr. Snow and his rheumatology colleagues cannot perform synovial fluid crystal analysis for their patients. The…
Dietary Recommendations for Psoriasis Patients
The National Psoriasis Foundation says weight loss and other dietary interventions may benefit psoriasis patients. New recommendations note the benefits of a gluten-free diet for patients who test positive for gluten sensitivity, but also found little evidence to support the use of fish oil supplements for psoriasis patients…
Statins Linked to Idiopathic Inflammatory Myositis
NEW YORK (Reuters Health)—Statin use is associated with an increased likelihood of developing idiopathic inflammatory myositis (IIM), researchers from Australia report. “[Although] the incidence of IIM is rare, with the increasing use of statins worldwide and the severity of this condition, this study highlights the need for increased awareness of the condition and the importance…
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