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Subcategories:Axial SpondyloarthritisClinical Criteria/GuidelinesGout and Crystalline ArthritisMyositisOsteoarthritis and Bone DisordersOther Rheumatic ConditionsPain SyndromesPediatric ConditionsPsoriatic ArthritisRheumatoid ArthritisSjögren’s DiseaseSoft Tissue PainSystemic Lupus ErythematosusSystemic SclerosisVasculitis

New Classification Criteria for SLE: Proposed ACR/EULAR Criteria aim for high sensitivity & specificity

Susan Bernstein  |  December 15, 2017

SAN DIEGO—The proposed classification criteria for systemic lupus erythematosus (SLE), supported but not yet approved by the ACR and EULAR, were debuted on Nov. 7 at the 2017 ACR/ARHP Annual Meeting. An international steering committee developed and validated the criteria, with patient input and the consensus of more than 150 global SLE experts. Rheumatology researchers…

The Pop Star Effect & Lupus: Celebrity Cred May Help Raise Awareness of Rheumatic Disease

Richard Quinn  |  December 15, 2017

This year, Selena Gomez underwent a kidney transplant as a result of damage from living with lupus. But how can this celebrity story aid rheumatologists? Many see it as an opportunity to raise awareness or create a dialogue with primary care physicians. But for lupus patients, it can be a reminder for them to take control of their own wellbeing, according to rheumatologist Susan Manzi, MD, MPH…

Older Women Should Not Take Hormones to Prevent Chronic Diseases

Will Boggs MD  |  December 14, 2017

(Reuters Health)— Postmenopausal women should not use hormone therapy to prevent chronic medical conditions, because the risk of significant side effects outweighs the unclear evidence of a benefit, according to a government-backed panel of experts. Most chronic conditions – coronary heart disease, dementia, stroke, fractures, and breast cancer, for example – are more common with…

Vitamin D-Metabolite Ratio Predicts Fracture Risk Better than 25(OH)D

Anne Harding  |  December 14, 2017

NEW YORK (Reuters Health)—Vitamin D-metabolite ratio (VMR) may be a better marker of bone health than 25(OH)D (25-hydroxyvitamin D), a new study suggests. “The parameter that’s currently used to assess vitamin D status, 25(OH)D, is a flawed measure because it doesn’t consistently associate with important bone outcomes like hip fractures,” Dr. Charles Ginsberg of Veterans…

Knee Surgery Outcomes Linked with Education Level

Lisa Rapaport  |  December 7, 2017

(Reuters Health)—Patients who live in low-income communities and lack a college education may have worse pain after knee replacement surgery than their more educated neighbors, a recent study suggests. Two years after total knee replacement surgeries, patients in poor communities who hadn’t gone to college had average pain scores that were about 10 points worse…

Safety, Tolerability & Pharmacodynamics of ABT-122 in Patients with RA

Arthritis & Rheumatology  |  December 5, 2017

The introduction of biologic disease-modifying anti-rheumatic drugs (DMARDs) has greatly expanded the treatment options for managing rheumatoid arthritis (RA). In many patients, biologic DMARDs improve clinical symptoms, improve function and slow disease progression. Biologic DMARDs are recommended as add-on treatment to conventional synthetic DMARDs, such as methotrexate (MTX) in patients who experienced an incomplete response…

Lacrimal & Tear Fluid Yield Clues to Dry Eye Disease

Lara C. Pullen, PhD  |  December 4, 2017

A recent study suggests novel markers of dry eye disease can be found in the lacrimal fluid and tear fluid of patients. Researchers analyzed the proteins in these fluids and found immune response-related proteins are upregulated at the protein level in lacrimal fluid of patients with dry eye disease and may be an important biomarker…

Multimodal Imaging May Uncover Neural Mechanisms in Pediatric Neuropsychiatric Lupus

Carina Stanton  |  December 1, 2017

In clinical practice, many unknowns exist about how SLE affects the brain—particularly in children. To help these young children battling pediatric SLE, Andrea Knight, MD, MSCE, is examining how advanced neuroimaging techniques may uncover potential inflammatory and non-inflammatory mechanisms of neuropsychiatric dysfunction in lupus…

Obesity’s Effects on Inflammatory Markers in Patients with RA

Arthritis Care & Research  |  November 29, 2017

New research has examined the effect of obesity on inflammatory markers, specifically C-reactive protein (CRP) level and erythrocyte sedimentation rate, in patients with rheumatoid arthritis (RA). Researchers found higher BMIs were associated with higher CRP levels in women both with and without RA, suggesting the phenomenon is related to adiposity and not an indication of disease activity. For men with RA, low BMI was associated with higher CRP levels, which proved to be RA-specific but not a direct causal effect of adiposity…

European Commission Approves Subcutaneous Belimumab for SLE; FDA Safety Alert for Febuxostat

Michele B. Kaufman, PharmD, BCGP  |  November 29, 2017

Subcutaneous belimumab has been approved in the EU to help treat patients with active autoantibody-positive SLE…

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