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Systemic Lupus Erythematosus

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Racial Disparities Result in Unprecedented Differences in Outcomes for SLE Patients

Eric L. Wise, MD, & W. Joseph McCune, MD  |  October 13, 2015

The differences between Caucasian and minority patients with lupus are striking: In almost all aspects of the disease, black, Hispanic and many Asian lupus patients do poorly compared with their white counterparts. Although racial disparities in outcomes in the practice of medicine are widespread, the scope and degree of the differences in lupus is, with…

Selena Gomez Says Suffered from Lupus, Underwent Chemotherapy

Reuters Staff  |  October 10, 2015

(Reuters)—Pop singer and actress Selena Gomez has revealed in an interview that she was diagnosed with the autoimmune disease lupus, which led to her canceling the end of her tour in 2013, but that the disease is now in remission. “I was diagnosed with lupus, and I’ve been through chemotherapy,” Gomez, 23, told Billboard magazine….

Tabalumab Modestly Effective in Systemic Lupus Erythematosus

Will Boggs, MD  |  October 7, 2015

NEW YORK (Reuters Health)—Tabalumab, a monoclonal antibody to B-cell activating factor, was modestly better than placebo in relieving symptoms of systemic lupus erythematosus (SLE), according to results from the ILLUMINATE-2 trial. “Lupus is a complicated disease that does not behave the same way in all patients who share the clinical symptoms,” Dr. Joan T. Merrill…

How Hospitals Rank in Treating Childhood-Onset SLE

Richard Quinn  |  October 6, 2015

A recent study of how medical facilities in three countries meet minimum care standards for patients with childhood-onset systemic lupus erythematosus found a wide variation in quality of care…

Figure 1: Hematoxylin & Eosin Staining

Systemic Lupus Erythematosus Without Kidney Involvement: A Case Report

Paul Hoover, MD, PhD, & Lindsey MacFarlane, MD  |  September 15, 2015

A 35-year-old female with a history of systemic lupus erythematosus (SLE) without kidney involvement was admitted to our hospital with low-grade fevers, headache, increasing lower extremity edema and elevated blood pressure. History She was first diagnosed with SLE as a teenager when she developed oral ulcers and pleuritic chest pain and tested positive for anti-Smith…

Understanding SLE-Associated Skin Injury May Open the Door to Therapies

Lara C. Pullen, PhD  |  September 7, 2015

In a recent review, researchers addressed skin injury in patients with SLE, discussing the effects of ultraviolet rays on the skin and the subsequent generation of autoantibodies. They concluded that UV rays activate immune cells where IgG has been deposited, resulting in inflammation…

The ACR’s Lupus Initiative Expands Training, Educational Resources

E. William St.Clair, MD  |  August 17, 2015

The Lupus Initiative (TLI) has been an emergent creation inside the American College of Rheumatology (ACR) for the past six years. In 2009, the Office of Minority Health and Office of Women’s Health (now called the Office of Health Disparities) solicited an application from the ACR to develop resources for educating non-rheumatologists, both in training…

Infection & Hospitalization in SLE

Arthritis Care & Research  |  August 4, 2015

From 1996–2011, the rates of hospitalization due to serious infectious diseases in patients with systemic lupus erythematosus (SLE) increased substantially, according to new research. In a retrospective data-driven study, researchers plotted and compared hospitalization and in-hospital mortality rates of SLE and non-SLE populations, determining the trends for the five most common infections…

New Study Examines Pregnancy Risk Factors for Patients with Lupus

Lara C. Pullen, PhD  |  July 20, 2015

Important new findings show that a majority of women with inactive or stable SLE can have successful pregnancies without experiencing flares and give birth to infants who survive the neonatal period…

The ACR’s State-of-the-Art Clinical Symposium: Experts Discuss Jakinibs, Osteoarthritis, Membranous Lupus Nephritis

Thomas R. Collins  |  July 14, 2015

CHICAGO—With the approval of the Jak inhibitors (i.e., jakinibs) tofacitinib and ruxolitinib—and others being investigated—rheumatologists need to arm themselves with an understanding of these drugs so they can think critically when evaluating them and deciding how to use them, said John O’Shea, MD, chief of the Molecular Immunology and Inflammation Branch of and scientific director…

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