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Axial Spondyloarthritis

Anatomy Insider / shutterstock.com

Gut Instinct: Ankylosing Spondylitis & the Microbiome

Jason Liebowitz, MD, FACR  |  October 3, 2019

CHICAGO—At the 2019 ACR State-of-the-Art Clinical Symposium, an annual gathering featuring talks by key opinion leaders on the most salient topics for practicing rheumatologists and healthcare providers, Jose U. Scher, MD, director of the Microbiome Center for Rheumatology and Autoimmunity at NYU Langone Medical Center, New York City, was the featured speaker. In his remarks,…

Imagining a Life Free from the Pain of Ankylosing Spondylitis

Lara C. Pullen, PhD  |  September 30, 2019

Dan Reynolds, the lead singer of the Grammy award-winning band Imagine Dragons, has partnered with Novartis to increase awareness of ankylosing spondylitis.

Chu KyungMin / shutterstock.com

The Bath Ankylosing Spondylitis Functional Index’s History & Patient View

Jason Liebowitz, MD, FACR  |  September 26, 2019

Sir William Osler, widely regarded as one of the greatest physicians of the 20th century, once said, “He who studies medicine without books sails an uncharted sea, but he who studies medicine without patients does not go to sea at all.”1 This sentiment is particularly true in the field of rheumatology, in which understanding the…

Ankylosing Spondylitis & Uveitis: An Ophthalmologist’s Perspective

Jason Liebowitz, MD, FACR  |  September 26, 2019

It’s often said the eyes are the window to the soul, and in the case of ankylosing spondylitis and other spondyloarthropathies, one can also say the eyes are the window to systemic disease. Although uveitis occurs in approximately 2–5% of patients with inflammatory bowel disease, 6–9% of patients with psoriatic arthritis and 25% of patients…

FDA Approves Ixekizumab for Treating Active Ankylosing Spondylitis

Michele B. Kaufman, PharmD, BCGP  |  September 23, 2019

Data from two phase 3 studies were used to support the FDA’s approval of ixekizumab for adults with ankylosing spondylitis…

Probing the Role of Genes & Microbiome in Ankylosing Spondylitis & RA

Lara C. Pullen, PhD  |  September 17, 2019

Researchers know human leukocyte antigen (HLA) molecules affect susceptibility to disease in general, and immunological disease in particular. In the case of ankylosing spondylitis (AS), the risk is primarily associated with HLA-B27, with smaller effects from other HLA alleles. Current thinking is that AS is caused by the presence of a genetically primed host because…

No Gain with Pain: Exercise & Physical Function in Patients with Rheumatic Disease

Jason Liebowitz, MD, FACR  |  September 9, 2019

Pain can deter patients with rheumatic disease from engaging in physical activity. But the latest research shows exercise helps reduce pain, & other influences may also affect patients’ activity levels, particularly after surgery…

Updates to Axial Spondyloarthritis Guideline

Carina Stanton  |  September 5, 2019

A 2019 update of the ACR’s previous clinical practice guideline on axial spondyloarthritis is now available online. Lead investigator Michael Ward, MD, shares advice for implementing the guideline updates, including those related to sequencing and tapering biologics, and knowing when to obtain images.

Peripheral Arthritis & Recent Onset Axial SpA: 5-Year Results from the DESIR Cohort

Lara C. Pullen, PhD  |  July 29, 2019

An analysis of follow-up data from the DESIR cohort showed patients with recent onset axial spondyloarthritis who experienced peripheral arthritis had worse symptoms and quality of life long term. In the study, peripheral arthritis was also associated with negative HLAB27, non-smoking and the presence of other peripheral disease manifestations…

Ankylosing Spondylitis Patients Report Improved Quality of Life with Bimekizumab

Michele B. Kaufman, PharmD, BCGP  |  July 8, 2019

Recent research shows bimekizumab may improve patient-reported outcomes and quality of life for ankylosing spondylitis (AS) patients…

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